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Results for "

pentafluorophenyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Bacterial (1) Biochemical Assay Reagents (4) CD38 (1) Endothelin Receptor (2) Fluorescent Dye (2) LYTACs (1) MOFs (3) PROTAC Linkers (1) Protease Activated Receptor (PAR) (2)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Infection (1) Metabolic Disease (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145368B

Tri-GalNAc(OAc)3-Perfluorophenyl	LYTACs	Metabolic Disease
Tri-GalNAc(OAc)3-Perfluorophenyl is a pentafluorophenyl modified Tri-GalNAc(OAc)3 (HY-148118), a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation.Tri-GalNAc(OAc)3-Perfluorophenyl can be used for the study of liver metabolism .

HY-D2320

ER Flipper-TR 28	Fluorescent Dye	Others
ER Flipper-TR 28 is a flipper probe with a small molecule fluorophore that can image membrane tension in the endoplasmic reticulum (ER). ER Flipper-TR 28 bears a pentafluorophenyl group and also reacts with protein thiolate on the ER surface facing the cytoplasm .

HY-P2496

*Endothelin 1 (swine, human), Alexa Fluor* 488-labeled**	Endothelin Receptor	Cardiovascular Disease
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ET_A and ET_B .

HY-P5372A

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-W112090

*Palladium meso-tetra(pentafluorophenyl)porphyrin* PdTFPP; 5,10,15,20-Tetrakis(pentafluorophenyl)-21H,23H-porphine palladium(II)	Fluorescent Dye	Others
Palladium meso-tetra(pentafluorophenyl)porphyrin (PdTFPP) derives from palladium(II), acting as a fluorescence-quenched optical probe and high-performance oxygen concentration sensor with outstanding photostability and antioxidant capacity. Palladium meso-tetra(pentafluorophenyl)porphyrin exhibits reduced luminescence intensity as dissolved oxygen concentration rises. Palladium meso-tetra(pentafluorophenyl)porphyrin can be applied for real-time monitoring of live-cell respiration, hypoxic tissue imaging, and nanofibrous organic semiconductors in photodetectors for ambient oxygen detection .

HY-W008843

*5,10,15,20-Tetrakis(pentafluorophenyl)-21h,23h-porphine* 5,10,15,20-Tetrakis(perfluorophenyl)porphyrin	MOFs	Others
5,10,15,20-Tetrakis(pentafluorophenyl)-21h,23h-porphine (5,10,15,20-Tetrakis(perfluorophenyl)porphyrin) is a metal-organic framework (MOF).

HY-W008896

*Tris(pentafluorophenyl)phosphine*	Biochemical Assay Reagents	Others
Tris(perfluorophenyl)phosphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P5372

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-W127854

*Bis(pentafluorophenyl) oxalate*	Biochemical Assay Reagents	Others
Bis(pentafluorophenyl) Oxalate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W034627

*5,10,15-Tri(pentafluorophenyl)corrole* meso-Tris(pentafluorophenyl)corrole	Biochemical Assay Reagents	Others
5,10,15-Tri(pentafluorophenyl)corrole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-W142171

*Nα-Fmoc-N(im)-trityl-L-histidine pentafluorophenyl* ester**	Amino Acid Derivatives	Others
Nα-Fmoc-N(im)-trityl-L-histidine pentafluorophenyl ester is a histidine derivative .

HY-141212

Hydroxy-PEG3-PFP ester pentafluorophenyl 3-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}propanoate	PROTAC Linkers	Cancer
Hydroxy-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W112940

*Pt(II) meso-Tetra(pentafluorophenyl)porphine* PT(II) Meso-tetra(pentafluorophenyl)porphine	MOFs	Others
Pt(II) meso-?Tetra(pentafluorophe?nyl)?porphine (PT(II) Meso-tetra(pentafluorophenyl)porphine) is a metal-organic framework (MOF).

HY-W588958

*5,10,15,20-Tetrakis(pentafluorophenyl)-21H,23H-porphyrin iron(III) chloride*	MOFs	Others
5,10,15,20-Tetrakis(pentafluorophenyl)-21H,23H-porphyrin iron(III) chloride is a metal-organic framework (MOF).

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

ER Flipper-TR 28	Fluorescent Dye
ER Flipper-TR 28 is a flipper probe with a small molecule fluorophore that can image membrane tension in the endoplasmic reticulum (ER). ER Flipper-TR 28 bears a pentafluorophenyl group and also reacts with protein thiolate on the ER surface facing the cytoplasm .

*Tris(pentafluorophenyl)phosphine*	Biochemical Assay Reagents
Tris(perfluorophenyl)phosphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

*Bis(pentafluorophenyl) oxalate*	Biochemical Assay Reagents
Bis(pentafluorophenyl) Oxalate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

*5,10,15-Tri(pentafluorophenyl)corrole* meso-Tris(pentafluorophenyl)corrole	Biochemical Assay Reagents
5,10,15-Tri(pentafluorophenyl)corrole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P2496

*Endothelin 1 (swine, human), Alexa Fluor* 488-labeled**	Endothelin Receptor	Cardiovascular Disease
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ET_A and ET_B .

HY-P5372A

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-P5373

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2	Peptides	Others
Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)

HY-P5372

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-W142171

*Nα-Fmoc-N(im)-trityl-L-histidine pentafluorophenyl* ester**	Amino Acid Derivatives	Others
Nα-Fmoc-N(im)-trityl-L-histidine pentafluorophenyl ester is a histidine derivative .

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

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