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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
pig kidney
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "pig kidney" in MCE Product Catalog:
Synonyms: Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine
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3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses) .
Synonyms: SQ 14551
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Captopril disulfide (SQ 14551) is an orally active disulfide dimer prodrug. Captopril disulfide is metabolized to Captopril and acts as a Bradykinin potentiator. Captopril disulfide enhances the vasodilatory effect of Bradykinin in anesthetized rats and the contractile response of isolated guinea pig ileum to Bradykinin. Captopril disulfide exhibits antihypertensive activity in spontaneously hypertensive rats. Captopril disulfide can be used in hypertension-related research .
Cat. No.: HY-W414548
CAS No.: 4725-24-0
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7α,27-Dihydroxycholesterol is an oxysterol, a human metabolite, and a ligand for EBI2 (GPR183), which is involved in lipid synthesis. 7α,27-Dihydroxycholesterol mediates the chemotaxis of cells expressing EBI2. 7α,27-Dihydroxycholesterol can be converted into 7α,27-dihydroxy-4-cholesten-3-one (HY-W414457), thereby inhibiting HMG-CoA reductase (HMGCR), the rate-limiting enzyme in cholesterol synthesis .
Cat. No.: HY-123189
CAS No.: 89139-28-6
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LY 171859 is a D2 receptor agonist with significant reductase activity. LY 171859 exhibits enzymatic activity in the cytoplasm of liver, lung, and kidney, and also contains significant reductase activity in rat and human blood. LY 171859 has higher hepatic reductase activity in guinea pigs, followed by hamsters, rabbits, rats, and mice. The substrate of LY 171859 shows an apparent Km of 5.6 μM. The reduction reaction of LY 171859 is NADPH-dependent with an apparent Km of 14.8 μM. Only the A-side hydrogen of NADPH is incorporated in the reduction product of LY 171859. The reaction of LY 171859 is inhibited by cyanide and thiol reagents, and phenobarbital does not induce its activity in rats .
Cat. No.: HY-Y0047S
Synonyms: Picolamine-d2; 3-Pyridinemethanamine-d2; Pyridin-3-ylmethanamine-d2
Cat. No.: HY-159196
CAS No.: 76338-50-6
Synonyms: 24-Oxocalcitriol
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Cat. No.: HY-165504
CAS No.: 126844-81-3
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Nagstatin is a naturally derived competitive inhibitor of N-acetyl-β-D-glucosaminidase (NAG-ase), with an IC50 of 0.0012 μg/mL and a Ki of 1.7×10 -8 M against porcine-derived enzyme. Nagstatin enhances cellular immune responses in normal mice and reactivates suppressed cellular immune responses in tumor-bearing mice. Nagstatin can be used in the research of various diseases such as diabetes and leukemia .
Cat. No.: HY-187102
CAS No.: 19866-38-7
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2-Hydrazinyl-3-methylbutanoic acid is a diamine oxidase (DAO) inhibitor. 2-Hydrazinyl-3-methylbutanoic acid acts as a non-competitive inhibitor of diamine oxidase (with histamine as the substrate), achieving an inhibition rate of up to 76%. This inhibition can be prevented by pre-incubation with 2-Ketoglutaric acid (HY-W013636) to form a non-inhibitory complex. 2-Hydrazinyl-3-methylbutanoic acid also inhibits glutamate decarboxylase and 5-hydroxytryptophan decarboxylase, and exhibits moderate inhibitory activity against monoamine oxidase. 2-Hydrazinyl-3-methylbutanoic acid can be used in studies related to amino acid metabolic enzymes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
