3-Picolylamine-d2
3-Picolylamine-d2 (Picolamine-d2) is the deuterium labeled 3-Picolylamine (HY-Y0047). 3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C6H6D2N2
- 분자량:110.15
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
신청
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 3731-52-0
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분자량 110.15
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화학식 C6H6D2N2
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SMILES
NC([2H])(C1=CC=CN=C1)[2H]
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Synonyms
Picolamine-d2; 3-Pyridinemethanamine-d2; Pyridin-3-ylmethanamine-d2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Park Y, et al. Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01006-19. [Content Brief]
[2]. BLASCHKO H, et al. Potentiation of the response to histamine by picolylamines. Br J Pharmacol Chemother. 1962 Dec;19(3):544-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-Picolylamine-d2 Related Classifications
HY-Y0047S Related Classifications
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