3731-52-0
Chemical Structure
3-Picolylamine
Synonym(s): Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine
- CAS No.: 3731-52-0
- Formula:C6H8N2
- Molecular Weight:108.14
IUPAC Name: pyridin-3-ylmethanamine
InChIKey: HDOUGSFASVGDCS-UHFFFAOYSA-N
SMILES: NCC1=CC=CN=C1
Biological Activity: 3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses)[1][2].
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3-Picolylamine | 99.73% | 3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses). | ||||||||||||||||||||
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3-Picolylamine-d2 | 3-Picolylamine-d2 (Picolamine-d2) is the deuterium labeled 3-Picolylamine (HY-Y0047). 3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses). | |||||||||||||||||||||
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References
- [1]. Park Y, et al. Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01006-19. [Content Brief]
- [2]. BLASCHKO H, et al. Potentiation of the response to histamine by picolylamines. Br J Pharmacol Chemother. 1962 Dec;19(3):544-51. [Content Brief]
