4725-24-0
Chemical Structure
7α,27-Dihydroxycholesterol
- CAS No.: 4725-24-0
- Formula:C27H46O3
- Molecular Weight:418.65
IUPAC Name: 1-(ethoxycarbonyl)piperidine-2-carboxylic acid
InChIKey: RXMHNAKZMGJANZ-DTTSCKGMSA-N
SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)CO)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=C[C@H]3O)C
Biological Activity: 7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC); it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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7α,27-Dihydroxycholesterol | 99.93% | 7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC); it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC). | ||||||||||||||||||||
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7α,27-Dihydroxycholesterol-d6 | 99.90% | 7α,27-Dihydroxycholesterol-d6 is deuterium labeled 7α,27-Dihydroxycholesterol. | ||||||||||||||||||||
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