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proanthocyanidin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) Bacterial (3) Bcl-2 Family (1) Biochemical Assay Reagents (1) Caspase (1) COX (3) Drug Derivative (2) Fungal (3) NF-κB (2) Parasite (1) Phospholipase (1) PKC (2) Reactive Oxygen Species (ROS) (4) Reference Standards (4) SOD (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (4) Endocrinology (1) Infection (4) Inflammation/Immunology (9) Metabolic Disease (2)

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Biochemical Assay Reagents

Natural
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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0796

Procyanidin B2 Maximum Cited Publications 17 Publications Verification proanthocyanidin B2	Reactive Oxygen Species (ROS)	Cancer
Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

HY-N0794

Proanthocyanidins 4 Publications Verification	Bacterial Fungal	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Proanthocyanidin (Procyanidin) are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancers agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy. .

HY-130237

Cinnamtannin B-1	Reactive Oxygen Species (ROS) NF-κB Apoptosis	Metabolic Disease Cancer
Cinnamtannin B-1 is a anthocyanidin. Cinnamtannin B-1 inhibits the osteoclast formation by inhibiting NF-kB signaling pathway and ROS generation. Cinnamtannin B-1 exhibits antioxidant, anti-inflammatory, antitumor and anti-platelet aggregation activities. Cinnamtannin B-1 is orally active .

HY-N2344

Procyanidin A1 2 Publications Verification proanthocyanidin A1	PKC	Inflammation/Immunology
Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca ²⁺ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects .

HY-N4146

Proanthocyanidin A4	Others	Inflammation/Immunology
Proanthocyanidin A4 is a polyphenol found in a variety of plants. Proanthocyanidin A4 possesses anti-inflammatory effects .

HY-N0796R

Procyanidin B2 (Standard) Maximum Cited Publications 17 Publications Verification proanthocyanidin B2 (Standard)	Reference Standards Reactive Oxygen Species (ROS)	Cancer
Procyanidin B2 (Standard) is the analytical standard of Procyanidin B2. This product is intended for research and analytical applications. Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

HY-W016729

4-(Dimethylamino)cinnamaldehyde 1 Publications Verification	Biochemical Assay Reagents	Others
4-(Dimethylamino)cinnamaldehyde is a reagent used for determining indole products of tryptophan decarboxylase and tryptophanase, and can also be used for quantifying proanthocyanidins in cranberry powder.

HY-N11100

Geranin A	Parasite	Infection
Geranin A is an A-type proanthocyanidin. Geranin A can be isolated from the antiprotozoal extract of Geranium niveum .

HY-N4145

Procyanidin A3 Cinnamtannin A3; Cinnamtannin II	Drug Derivative Bacterial Fungal	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Procyanidin A3 (Cinnamtannin A3; Cinnamtannin II) is a sub class of Proanthocyanidins (HY-N0794). Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy .

HY-N4146R

Proanthocyanidin A4 (Standard)	Reference Standards Others	Inflammation/Immunology
Proanthocyanidin A4 (Standard) is the analytical standard of Proanthocyanidin A4. This product is intended for research and analytical applications. Proanthocyanidin A4 is a polyphenol found in a variety of plants. Proanthocyanidin A4 possesses anti-inflammatory effects .

HY-N16480

Lindetannin Lindetannin trimer	Drug Derivative Bacterial Fungal	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Lindetannin (Lindetannin trimer) is an A-type trimer of proanthocyanidin (HY-N0794) found in the bark of Cinnamomum trees. Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy .

HY-N2344R

Procyanidin A1 (Standard) proanthocyanidin A1 (Standard)	Reference Standards PKC	Inflammation/Immunology
Procyanidin A1 (Standard) is the analytical standard of Procyanidin A1. This product is intended for research and analytical applications. Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects .

HY-N11101

Procyanidin A5'	Others	Others
Procyanidin A5' is A dimerized proanthocyanidin type A .

HY-N13200

Cranberry Extract	COX	Others
Cranberry Extract is the extract of Cranberry, with content of 25% -50% Proanthocyanidins.

HY-N7709

Cinchonain IIb	Others	Cardiovascular Disease
Cinchonain IIb is a proanthocyanidin. Cinchonain IIb has the effect of rational utilization of decreased cardiac function. Cinchonain IIb is isolated from natural hawthorn (Crataegus spp. ) .

HY-N16482

Cassiatannin A	COX	Inflammation/Immunology
Cassiatannin A is a tetramer of proanthocyanidin (HY-N0794) found in Cinnamomum cassia. Cassiatannin A shows COX-2 inhibitor activity with inhibition rate of 38, 52 and 97% at 10, 100 and 1000 μg/mL. Cassiatannin A can be used for the research of inflammation .

HY-N16481

Parameritannin A-1	COX Phospholipase	Inflammation/Immunology
Parameritannin A-1 is a tetrameric proanthocyanidin (PAC) that can be isolated from the bark of Parameria laevigata Moldenke (Apocynaceae). Parameritannin A-1 is a COX-2 inhibitor. Parameritannin A-1 also inhibits the activity of phospholipase A₂ (PLA₂) .

HY-130237R

Cinnamtannin B-1 (Standard)	Reference Standards Reactive Oxygen Species (ROS) NF-κB Apoptosis	Metabolic Disease Cancer
Cinnamtannin B-1 (Standard) is the analytical standard of Cinnamtannin B-1. This product is intended for research and analytical applications. Cinnamtannin B-1 is a anthocyanidin. Cinnamtannin B-1 inhibits the osteoclast formation by inhibiting NF-kB signaling pathway and ROS generation. Cinnamtannin B-1 exhibits antioxidant, anti-inflammatory, antitumor and anti-platelet aggregation activities. Cinnamtannin B-1 is orally active .

HY-N18905

α-D-Glucosyl hesperidin	Apoptosis Bcl-2 Family Caspase SOD	Endocrinology
α-D-Glucosyl hesperidin is an orally effective structural modification derivative of Hesperidin (HY-15337) with anti-apoptotic (apoptosis) and antioxidant activities. α-D-Glucosyl hesperidin upregulates the expression of the Bcl-2 gene, while downregulating the expressions of the Bax and caspase-3 genes. α-D-Glucosyl hesperidin increases total antioxidant capacity, SOD and catalase levels, and decreases malondialdehyde and glutathione levels. α-D-Glucosyl hesperidin improves sperm motility, viability and plasma membrane function, while restoring reproductive organ weight and seminiferous tubule structure. α-D-Glucosyl hesperidin increases fertility index and exerts a synergistic protective effect with Proanthocyanidins (HY-N0794) in male rats with testicular ischemia-reperfusion injury. α-D-Glucosyl hesperidin can be used in the research of testicular ischemia-reperfusion injury .

Cat. No.	Product Name	Type

HY-W016729

4-(Dimethylamino)cinnamaldehyde 1 Publications Verification	Biochemical Assay Reagents
4-(Dimethylamino)cinnamaldehyde is a reagent used for determining indole products of tryptophan decarboxylase and tryptophanase, and can also be used for quantifying proanthocyanidins in cranberry powder.

Procyanidin B2 Maximum Cited Publications 17 Publications Verification proanthocyanidin B2	Flavonoids other families Functional Molecules Classification of Application Fields Research of Health Products Phenols Polyphenols Plants Biflavones Disease Research Fields Source Classification Cancer	Reactive Oxygen Species (ROS)
Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

Proanthocyanidins 4 Publications Verification	Cardiovascular Disease Classification of Application Fields Plants Infection Flavonoids other families Functional Molecules Research of Health Products Phenols Polyphenols Biflavones Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Fungal
Proanthocyanidin (Procyanidin) are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancers agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy. .

Cinnamtannin B-1	Anthocyans Flavonoids other families Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Reactive Oxygen Species (ROS) NF-κB Apoptosis
Cinnamtannin B-1 is a anthocyanidin. Cinnamtannin B-1 inhibits the osteoclast formation by inhibiting NF-kB signaling pathway and ROS generation. Cinnamtannin B-1 exhibits antioxidant, anti-inflammatory, antitumor and anti-platelet aggregation activities. Cinnamtannin B-1 is orally active .

Procyanidin A1 2 Publications Verification proanthocyanidin A1	Flavonoids other families Functional Molecules Classification of Application Fields Research of Health Products Phenols Polyphenols Plants Biflavones Inflammation/Immunology Disease Research Fields Source Classification	PKC
Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca ²⁺ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects .

Proanthocyanidin A4	Classification of Application Fields Vitis vinifera cv. Zalema Plants Vitaceae Flavonoids Functional Molecules Research of Health Products Phenols Polyphenols Biflavones Inflammation/Immunology Disease Research Fields Source Classification	Others
Proanthocyanidin A4 is a polyphenol found in a variety of plants. Proanthocyanidin A4 possesses anti-inflammatory effects .

Procyanidin B2 (Standard) Maximum Cited Publications 17 Publications Verification proanthocyanidin B2 (Standard)	Flavonoids other families Functional Molecules Classification of Application Fields Research of Health Products Phenols Plants Disease Research Fields Source Classification Cancer	Reference Standards Reactive Oxygen Species (ROS)
Procyanidin B2 (Standard) is the analytical standard of Procyanidin B2. This product is intended for research and analytical applications. Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

Geranin A	Phenols Polyphenols Plants Geranium niveum S.Watson Geraniaceae Source Classification	Parasite
Geranin A is an A-type proanthocyanidin. Geranin A can be isolated from the antiprotozoal extract of Geranium niveum .

Procyanidin A3 Cinnamtannin A3; Cinnamtannin II	Structural Classification Cinnamomum cassia (L.) D. Don Phenols Polyphenols Plants Lauraceae Source Classification	Drug Derivative Bacterial Fungal
Procyanidin A3 (Cinnamtannin A3; Cinnamtannin II) is a sub class of Proanthocyanidins (HY-N0794). Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy .

Proanthocyanidin A4 (Standard)	Structural Classification Flavonoids Vitis vinifera cv. Zalema Phenols Polyphenols Plants Vitaceae Biflavones Source Classification	Reference Standards Others
Proanthocyanidin A4 (Standard) is the analytical standard of Proanthocyanidin A4. This product is intended for research and analytical applications. Proanthocyanidin A4 is a polyphenol found in a variety of plants. Proanthocyanidin A4 possesses anti-inflammatory effects .

Lindetannin Lindetannin trimer	Structural Classification Phenols Polyphenols Plants Lauraceae Lindera aggregata (Sims) Kosterm. Source Classification	Drug Derivative Bacterial Fungal
Lindetannin (Lindetannin trimer) is an A-type trimer of proanthocyanidin (HY-N0794) found in the bark of Cinnamomum trees. Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy .

Procyanidin A1 (Standard) proanthocyanidin A1 (Standard)	Structural Classification Flavonoids other families Phenols Polyphenols Plants Biflavones Source Classification	Reference Standards PKC
Procyanidin A1 (Standard) is the analytical standard of Procyanidin A1. This product is intended for research and analytical applications. Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects .

Procyanidin A5'	Prunus spinosa L. Rosaceae Phenols Polyphenols Plants Source Classification	Others
Procyanidin A5' is A dimerized proanthocyanidin type A .

Cinchonain IIb	Crataegus monogyna Jacq. Rosaceae Phenols Polyphenols Plants Source Classification	Others
Cinchonain IIb is a proanthocyanidin. Cinchonain IIb has the effect of rational utilization of decreased cardiac function. Cinchonain IIb is isolated from natural hawthorn (Crataegus spp. ) .

Cassiatannin A	Structural Classification Cinnamomum cassia (L.) D. Don Phenols Polyphenols Plants Lauraceae Source Classification	COX
Cassiatannin A is a tetramer of proanthocyanidin (HY-N0794) found in Cinnamomum cassia. Cassiatannin A shows COX-2 inhibitor activity with inhibition rate of 38, 52 and 97% at 10, 100 and 1000 μg/mL. Cassiatannin A can be used for the research of inflammation .

Parameritannin A-1	Apocynaceae Structural Classification Phenols Polyphenols Parameria laevigata (Juss.) Moldenke Plants Source Classification	COX Phospholipase
Parameritannin A-1 is a tetrameric proanthocyanidin (PAC) that can be isolated from the bark of Parameria laevigata Moldenke (Apocynaceae). Parameritannin A-1 is a COX-2 inhibitor. Parameritannin A-1 also inhibits the activity of phospholipase A₂ (PLA₂) .

Cinnamtannin B-1 (Standard)	Structural Classification Anthocyans Flavonoids other families Phenols Polyphenols Plants Source Classification	Reference Standards Reactive Oxygen Species (ROS) NF-κB Apoptosis
Cinnamtannin B-1 (Standard) is the analytical standard of Cinnamtannin B-1. This product is intended for research and analytical applications. Cinnamtannin B-1 is a anthocyanidin. Cinnamtannin B-1 inhibits the osteoclast formation by inhibiting NF-kB signaling pathway and ROS generation. Cinnamtannin B-1 exhibits antioxidant, anti-inflammatory, antitumor and anti-platelet aggregation activities. Cinnamtannin B-1 is orally active .

α-D-Glucosyl hesperidin	Structural Classification Flavonoids Flavonones Endogenous metabolite Source Classification	Apoptosis Bcl-2 Family Caspase SOD
α-D-Glucosyl hesperidin is an orally effective structural modification derivative of Hesperidin (HY-15337) with anti-apoptotic (apoptosis) and antioxidant activities. α-D-Glucosyl hesperidin upregulates the expression of the Bcl-2 gene, while downregulating the expressions of the Bax and caspase-3 genes. α-D-Glucosyl hesperidin increases total antioxidant capacity, SOD and catalase levels, and decreases malondialdehyde and glutathione levels. α-D-Glucosyl hesperidin improves sperm motility, viability and plasma membrane function, while restoring reproductive organ weight and seminiferous tubule structure. α-D-Glucosyl hesperidin increases fertility index and exerts a synergistic protective effect with Proanthocyanidins (HY-N0794) in male rats with testicular ischemia-reperfusion injury. α-D-Glucosyl hesperidin can be used in the research of testicular ischemia-reperfusion injury .

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Inhibitors & Agonists

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Natural
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