Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
pyrimidine ring
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "pyrimidine ring" in MCE Product Catalog:
3
3
Research Areas:
Guanine hydrochloride is one of the fundamental components of nucleic acids (DNA and RNA). Guanine hydrochloride is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine hydrochloride has the potential to serve as a large-capacity N pool. Guanine hydrochloride has cytotoxic, antinociceptive and neuroprotective effects .
Cat. No.: HY-B1449S11
Synonyms: β-Uridine-13C9
Cat. No.: HY-Y1055S
CAS No.: 201489-20-5
Cat. No.: HY-Y1055S3
CAS No.: 168566-53-8
Cat. No.: HY-W751165
CAS No.: 202406-84-6
Synonyms: β-Uridine-13C9,15N2
Cat. No.: HY-Y1055S1
CAS No.: 202407-12-3
Cat. No.: HY-B1449S12
Synonyms: β-Uridine-d12
Cat. No.: HY-W777809
CAS No.: 1246814-70-9
Cat. No.: HY-100644
CAS No.: 27653-68-5
Synonyms: Trimethoprim 1-N-oxide
Target:
Research Areas:
Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes .
Cat. No.: HY-Y1055S4
Cat. No.: HY-W778114
CAS No.: 1207525-05-0
Cat. No.: HY-155817
Target:
Research Areas:
UNC7096 (compound 53) is a biotinylated affinity reagent. The phenyl ring of UNC7096 replaces the pyrimidine ring in UNC6934 (HY-145103) and introduces biotin at the para position of the phenyl ring, which has a high binding affinity to the NSD2-PWWP1 domain (Kd=46 nM). UNC7096 blocks the interaction between NSD2-PWWP1 and nucleosomal H3K36me2 by occupying the methyl-lysine binding pocket of NSD2-PWWP1. This binding is achieved by covalent binding through the formation of hydrogen bonds and a specific aromatic cage structure. UNC7096 can be used to capture proteins that interact with the NSD2-PWWP1 domain to further analyze the biological significance of these interactions .
Cat. No.: HY-Y1055S2
Cat. No.: HY-Y1055S6
Cat. No.: HY-W742094
CAS No.: 6092-18-8
Cycotiamine is an S-acylated thiamine derivative with antiplasmodial activity. Cycotiamine inhibits the proliferation of Plasmodium falciparum and Plasmodium knowlesi. Cycotiamine can be used in malaria-related research .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
