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Results for "

pyrimidine ring

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

3

Natural
Products

11

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y1055
    Guanine
    3 Publications Verification

    DNA/RNA Synthesis Endogenous Metabolite Infection Neurological Disease Cancer
    Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine
  • HY-Y1055A
    Guanine hydrochloride
    3 Publications Verification

    Endogenous Metabolite DNA/RNA Synthesis Infection Neurological Disease Cancer
    Guanine hydrochloride is one of the fundamental components of nucleic acids (DNA and RNA). Guanine hydrochloride is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine hydrochloride has the potential to serve as a large-capacity N pool. Guanine hydrochloride has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine hydrochloride
  • HY-126061

    Biochemical Assay Reagents Drug Metabolite Others
    1,7-Dimethyluric acid is an N-methylated uric acid and purine derivative, as well as a caffeine metabolite. When 1,7-Dimethyluric acid is acted upon by peroxidase in the presence of H2O2, it follows the same oxidation pathway to generate a UV-absorbing intermediate, which decays via first-order kinetics. 1,7-Dimethyluric acid can adsorb onto pyrolytic graphite electrodes, but not onto glassy carbon electrodes or platinum electrodes. The N-methylation modification of its pyrimidine ring prevents ring contraction of the diol intermediate, and no NMR evidence of O-alkylation is observed during propylation under the test conditions .
    1,7-Dimethyluric acid
  • HY-B1449S11

    β-Uridine-13C9

    Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog Cancer
    Uridine- 13C9 (β-Uridine- 13C9) is a 13C9-labeled form of Uridine (HY-B1449). Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .
    Uridine-13C9
  • HY-Y1055S3

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Guanine- 15N5 is 15N labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine-15N5
  • HY-Y1055S

    DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Guanine- 13C is the 13C labeled Guanine (HY-Y1055) . Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine-13C
  • HY-Y1055R

    Reference Standards DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Guanine (Standard) is the analytical standard of Guanine (HY-Y1055). This product is intended for research and analytical applications. Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine (Standard)
  • HY-W751165

    β-Uridine-13C9,15N2

    Endogenous Metabolite Nucleoside Antimetabolite/Analog Isotope-Labeled Compounds Cancer
    Uridine-13C9,15N2 (β-Uridine-13C9,15N2) is 13C and 15N labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .
    Uridine-13C9,15N2
  • HY-Y1055S1

    DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Guanine- 13C, 15N2 is the 13C and 15N labeled Guanine (HY-Y1055) . Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine-13C,15N2
  • HY-B1449S12

    β-Uridine-d12

    Endogenous Metabolite Nucleoside Antimetabolite/Analog Isotope-Labeled Compounds Cancer
    Uridine-d12 (β-Uridine-d12) is the deuterium labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .
    Uridine-d12
  • HY-W777809

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Cancer
    Guanine- 13C2, 15N is the 13C- and 15N-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine-13C2,15N
  • HY-100644

    Trimethoprim 1-N-oxide

    Drug Metabolite Infection
    Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes .
    Trimethoprim N-oxide
  • HY-Y1055S4

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Guanine- 13C5 is 13C-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine-13C5
  • HY-155817

    Histone Methyltransferase Others
    UNC7096 (compound 53) is a biotinylated affinity reagent. The phenyl ring of UNC7096 replaces the pyrimidine ring in UNC6934 (HY-145103) and introduces biotin at the para position of the phenyl ring, which has a high binding affinity to the NSD2-PWWP1 domain (Kd=46 nM). UNC7096 blocks the interaction between NSD2-PWWP1 and nucleosomal H3K36me2 by occupying the methyl-lysine binding pocket of NSD2-PWWP1. This binding is achieved by covalent binding through the formation of hydrogen bonds and a specific aromatic cage structure. UNC7096 can be used to capture proteins that interact with the NSD2-PWWP1 domain to further analyze the biological significance of these interactions .
    UNC7096
  • HY-W778114

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Cancer
    Guanine- 13C2, 15N is the 13C- and 15N-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine-13C2,7-15N
  • HY-Y1055S2

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Guanine- 13C5, 15N5 is 13C and 15N-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine-13C5,15N5
  • HY-Y1055S6

    Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Guanine-d5 is the deuterium labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine-d5
  • HY-W742094

    Parasite Infection
    Cycotiamine is an S-acylated thiamine derivative with antiplasmodial activity. Cycotiamine inhibits the proliferation of Plasmodium falciparum and Plasmodium knowlesi. Cycotiamine can be used in malaria-related research .
    Cycotiamine

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