73-40-5
73-40-5
Chemical Structure
Guanine
- CAS No.: 73-40-5
- Formula:C5H5N5O
- Molecular Weight:151.13
IUPAC Name: 2-amino-3,7-dihydro-6H-purin-6-one
InChIKey: UYTPUPDQBNUYGX-UHFFFAOYSA-N
SMILES: O=C1N=C(N)NC2=C1NC=N2
Biological Activity: Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Guanine | 98.0% | Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | ||||||||||||||||||||
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Guanine (Standard) | 99.99% | Guanine (Standard) is the analytical standard of Guanine (HY-Y1055). This product is intended for research and analytical applications. Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | ||||||||||||||||||||
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Guanine-13C,15N2 | 98.6% | Guanine-13C,15N2 is the 13C and 15N labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | ||||||||||||||||||||
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Guanine-13C5 | 95.0% | Guanine-13C5 is 13C-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | ||||||||||||||||||||
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Guanine-15N5 | 98% | Guanine-15N5 is 15N labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | ||||||||||||||||||||
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Guanine-13C2,7-15N | Guanine-13C2,15N is the 13C- and 15N-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | |||||||||||||||||||||
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Guanine-13C2,15N | Guanine-13C2,15N is the 13C- and 15N-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | |||||||||||||||||||||
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Guanine-13C | 99.5% | Guanine-13C is the 13C labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | ||||||||||||||||||||
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Guanine-d5 | Guanine-d5 is the deuterium labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects. | |||||||||||||||||||||
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2-(Methylamino)-1H-purin-6(7H)-one | 98.0% | 2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids. | ||||||||||||||||||||
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Dezaguanine | Dezaguanine is a purine analog. Dezaguanine exhibits antitumor activity in leukemia and breast cancer cells. Dezaguanine can be used in cancer-related research. | |||||||||||||||||||||
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Xanthopterin | 98.87% | Xanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm. Xanthopterin (XPT) causes renal growth and hypertrophy in rat. Xanthopterin inhibits RNA synthesis. | ||||||||||||||||||||
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Isoguanine | 99.64% | Isoguanine is a purine base that is an isomer of Guanine. A building block in organic synthesis. | ||||||||||||||||||||
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8-Aminoguanine | 97.19% | 8-Aminoguanine is a endogenous purine. 8-Aminoguanine inhibits PNPase (purine nucleoside phosphorylase). 8-Aminoguanine induces diuresis/natriuresis/glucosuria. | ||||||||||||||||||||
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8-Azaguanine (Standard) | ≥98% | 8-Azaguanine (Standard) is the analytical standard of 8-Azaguanine. This product is intended for research and analytical applications. 8-Azaguanine is a purine analogue that shows antineoplastic activity. 8-Azaguanine functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. | ||||||||||||||||||||
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3-Methylguanine | 3-Methylguanine is a DNA damage product caused by alkylation. 3-Methylguanine is cytotoxic and causes cell death by inhibiting DNA replication. 3-Methylguanine can be used to study the mechanism of DNA damage caused by alkylating agents and its repair pathways. | |||||||||||||||||||||
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Guanine hydrochloride | 98.78% | Guanine hydrochloride is one of the fundamental components of nucleic acids (DNA and RNA). Guanine hydrochloride is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine hydrochloride has the potential to serve as a large-capacity N pool. Guanine hydrochloride has cytotoxic, antinociceptive and neuroprotective effects. | ||||||||||||||||||||
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References
- [1]. Mojzeš P, et al. Guanine, a high-capacity and rapid-turnover nitrogen reserve in microalgal cells. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32722-32730. [Content Brief]
- [2]. Chauhan V, et al. In Silico Discovery and Validation of Amide Based Small Molecule Targeting the Enzymatic Site of Shiga Toxin. J Med Chem. 2016 Dec 8;59(23):10763-10773. [Content Brief]
- [3]. Messina E, et al. Guanine nucleotide depletion triggers cell cycle arrest and apoptosis in human neuroblastoma cell lines. Int J Cancer. 2004 Mar 1;108(6):812-7. [Content Brief]
- [4]. de Oliveira ED, et al. Mechanisms involved in the antinociception induced by spinal administration of inosine or guanine in mice. Eur J Pharmacol. 2016 Feb 5;772:71-82. [Content Brief]
