8-Aminoguanine
Based on 1 Customer Validation
8-Aminoguanine is a endogenous purine. 8-Aminoguanine inhibits PNPase (purine nucleoside phosphorylase). 8-Aminoguanine induces diuresis/natriuresis/glucosuria.
For research use only. We do not sell to patients.
- Purity: 97.19%
- CAS No.: 28128-41-8
- Formula: C5H6N6O
- Molecular Weight:166.14
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MOLT-4 | IC50 |
~400 μM
Compound: 1a
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Cytotoxicity was evaluated against human MOLT-4 T-lymphoblasts (absence of 10 uM 2'-deoxyguanosine (Wo/GdR))
Cytotoxicity was evaluated against human MOLT-4 T-lymphoblasts (absence of 10 uM 2'-deoxyguanosine (Wo/GdR))
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[PMID: 3091835] |
| MOLT-4 | IC50 |
>500 μM
Compound: 6
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Compound was tested for inhibition of MOLT-4 cell growth using human lymphoblast cytotoxicity assay in the absence of 2''-deoxy guanosine, cytotoxicity determined by monitoring uptake of [3H]thymidine
Compound was tested for inhibition of MOLT-4 cell growth using human lymphoblast cytotoxicity assay in the absence of 2''-deoxy guanosine, cytotoxicity determined by monitoring uptake of [3H]thymidine
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[PMID: 3093681] |
| MOLT-4 | IC50 |
1.6 μM
Compound: 6
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Compound was tested for inhibition of MOLT-4 cell growth using human lymphoblast cytotoxicity assay in the presence of 2''-deoxy guanosine, cytotoxicity determined by monitoring uptake of [3H]thymidine
Compound was tested for inhibition of MOLT-4 cell growth using human lymphoblast cytotoxicity assay in the presence of 2''-deoxy guanosine, cytotoxicity determined by monitoring uptake of [3H]thymidine
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[PMID: 3093681] |
| MOLT-4 | IC50 |
2.35 μM
Compound: 1a
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Cytotoxicity was evaluated against human MOLT-4 T-lymphoblasts (presence of 10 uM 2'-deoxyguanosine (W/GdR))
Cytotoxicity was evaluated against human MOLT-4 T-lymphoblasts (presence of 10 uM 2'-deoxyguanosine (W/GdR))
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[PMID: 3091835] |
Chemical Information
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CAS No. 28128-41-8
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Appearance Solid
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Molecular Weight 166.14
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Formula C5H6N6O
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Color Light yellow to yellow
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SMILES
O=C1NC(N)=NC2=C1N=C(N)N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
0.1 M NaOH : 2 mg/mL (12.04 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 0.1 M NaOH | 1 mM | 6.0190 mL | 30.0951 mL | 60.1902 mL | 150.4755 mL |
| 5 mM | 1.2038 mL | 6.0190 mL | 12.0380 mL | 30.0951 mL | |
| 10 mM | 0.6019 mL | 3.0095 mL | 6.0190 mL | 15.0476 mL |
8-Aminoguanine Related Classifications
HY-139037 Related Classifications
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