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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
quinolinone
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "quinolinone" in MCE Product Catalog:
Cat. No.: HY-34494
CAS No.: 15450-76-7
Synonyms: 2,8-Dihydroxyquinoline; 8-Hydroxycarbostyril
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8-Hydroxy-2(1H)-quinolinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Cat. No.: HY-W010130
CAS No.: 22246-18-0
Synonyms: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
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7-Hydroxy- 3, 4- dihydro- 2(1H) - quinolinone (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone) is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B .
Cat. No.: HY-W344938
CAS No.: 8004-92-0
Synonyms: Quinoline yellow
Cat. No.: HY-N4164
CAS No.: 80554-58-1
Cat. No.: HY-34763
CAS No.: 70500-72-0
Synonyms: 7-Hydroxyquinolinone; 2,7-Dihydroxyquinoline
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7-Hydroxycarbostyril (7-Hydroxy-2(1H)-quinolinone) (Compound 7) is a quinolinone derivative. 7-Hydroxycarbostyril can be used for synthesis of Brexpiprazole (HY-15780). Brexpiprazole, a typical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor .
Cat. No.: HY-158721
CAS No.: 1214268-60-6
Synonyms: Marinamide
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Cat. No.: HY-150583
CAS No.: 2416338-24-2
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Chitin synthase inhibitor 2 (compound 2b) is a potent inhibitor of chitin synthase with the IC50 value of 0.09 mM and the Ki value of 0.12 mM. Chitin synthase inhibitor 2 has antimicrobial activities in vitro and shows synergistic or additive effects with fluconazole or polyoxin B .
Cat. No.: HY-N1637
CAS No.: 22048-98-2
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Cat. No.: HY-N10456
CAS No.: 98393-27-2
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Cat. No.: HY-N10907
CAS No.: 182056-11-7
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Cat. No.: HY-116574
CAS No.: 132587-63-4
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Cat. No.: HY-126467
CAS No.: 194037-25-7
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TA-270, a novel quinolinone derivative, is a potent inhibitor of 5-lipoxygenase that plays an important role in asthma research .
Cat. No.: HY-167079
CAS No.: 128667-63-0
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OPC-18750 is a novel positive inotropic agent and 2(lH)-quinolinone derivative. OPC-18750 displays positive inotropic and coronary vasodilating effects .
Cat. No.: HY-W344938R
CAS No.: 8004-92-0
Synonyms: Quinoline yellow (Standard)
Cat. No.: HY-W010130R
CAS No.: 22246-18-0
Synonyms: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone (Standard)
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7-Hydroxy-3,4-dihydro-2(1H)-quinolinone (Standard) is the analytical standard of 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone. This product is intended for research and analytical applications. 7-?Hydroxy-?3,?4-?dihydro-?2(1H)?-?quinolinone (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone) is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B .
Cat. No.: HY-402321
CAS No.: 80554-60-5
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Cat. No.: HY-W002905R
CAS No.: 54197-66-9
Synonyms: 6-Hydroxyl-3.4-dihydro-2-(1H)-quinolinone (Standard)
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6-Hydroxy-3,4-dihydroquinolin-2(1H)-one (Standard) is the analytical standard of 6-Hydroxy-3,4-dihydroquinolin-2(1H)-one. This product is intended for research and analytical applications.
Cat. No.: HY-179529
EGFR/InhA-IN-1 (Compound 15) is an inhibitor of the anti-cancer target EGFR tyrosine kinase (1M17) (Ki = 0.05 μM) and the anti-tuberculosis target InhA enzyme (1OUZ) (Ki = 0.02 μM). EGFR/InhA-IN-1 exhibits anti-proliferative activity against A549 cells, with an IC50 of 10.38 μM. EGFR/InhA-IN-1 has inhibitory activity against Mycobacterium tuberculosis H37Rv, with a MIC of 6.25 μM. EGFR/InhA-IN-1 can be used for research on non-small cell lung cancer and Mycobacterium tuberculosis infection .
Cat. No.: HY-182449
CAS No.: 2647503-59-9
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CCT365386 is a BCL6 inhibitor. CCT365386 serves as an optimized lead compound for cell-active BCL6 degraders (including CCT369260 (HY-129188)). CCT365386 can be used in the research of B-cell lymphoma .
Cat. No.: HY-180913
CAS No.: 2762499-38-5
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FQI2-34 is an orally active TFCP2 (LSF) small molecule allosteric inhibitor. FQI2-34 directly binds to the LSF protein (Ki = 63 nM), inhibits the oligomerization of LSF, efficiently suppresses the transcriptional activity of LSF (IC₅₀ = 48 nM), and interferes with the SF-DNA interaction. FQI2-34 exhibits significant anti-proliferative activity against Huh7 cells and induces tumor regression in mouse models. FQI2-34 can be used for research on liver cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
