2416338-24-2
2416338-24-2
Chemical Structure
Chitin synthase inhibitor 2
- CAS No.: 2416338-24-2
- Formula:C20H19N3O3
- Molecular Weight:349.38
IUPAC Name: N1-(2-methoxyphenyl)-N4-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)fumaramide
InChIKey: IBXKKDCQPPLETQ-MDZDMXLPSA-N
SMILES: O=C(NC1C(NC2=C(C=CC=C2)C1)=O)/C=C/C(NC3=CC=CC(C)=C3)=O
Biological Activity: Chitin synthase inhibitor 2 (compound 2b) is a potent inhibitor of chitin synthase with the IC50 value of 0.09 mM and the Ki value of 0.12 mM. Chitin synthase inhibitor 2 has antimicrobial activities in vitro and shows synergistic or additive effects with fluconazole or polyoxin B[1].
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Chitin synthase inhibitor 2 | Chitin synthase inhibitor 2 (compound 2b) is a potent inhibitor of chitin synthase with the IC50 value of 0.09 mM and the Ki value of 0.12 mM. Chitin synthase inhibitor 2 has antimicrobial activities in vitro and shows synergistic or additive effects with fluconazole or polyoxin B. | |||||||||||||||||||||
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