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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
sedative hypnotic
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "sedative hypnotic" in MCE Product Catalog:
1
Category:
Target:
1
1 Cited Publications
Art. -Nr.: HY-W008645
CAS. Nr.: 131733-92-1
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Forschungsgebiete:
NCS-382 (sodium) is a potent GABA receptor antagonist. NCS-382 (sodium) has anti-sedative and anti-hypnotic activities and can be used in research related to neurological diseases .
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Forschungsgebiete:
Alimemazine hemitartrate (Trimeprazine hemitartrate) is an antagonist of the histamine (HA) receptor that can be taken orally and also acts as a partial agonist at other GPCR receptors. Alimemazine hemitartrate has effects that include anti-serotonin, antispasmodic, antihistamine, sedation, hypnotic, antiviral, and anti-nausea properties. Alimemazine hemitartrate promotes the growth of pancreatic β-cells in mice and improves diabetes in mice .
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Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .
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Forschungsgebiete:
Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .
Art. -Nr.: HY-121890
CAS. Nr.: 66857-17-8
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Etoxybamide is a sedative. Etoxybamide has sedative and hypnotic effects .
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Acecarbromal (Acetylcarbromal) is a Urea (HY-Y0271) derivative. Acecarbromal is a hypnotic and sedative agent .
Synonyms: Anticonvulsant 7903
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Forschungsgebiete:
Lvguidingan is a potent anticonvulsant agent. Lvguidingan also has sedative-hypnotic, tranquilizing, and muscle-relaxing actions. Lvguidingan can be used as antiepileptic agent .
Art. -Nr.: HY-125508
CAS. Nr.: 162883-07-0
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CCD-3693 is an orally active GABA receptor agonist. CCD-3693 has anxiolytic, anticonvulsant and sedative hypnotic activities and can be used in research related to neurological diseases .
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Pyrithyldione is a sedative-hypnotic agent that induces agranulocytosis .
Art. -Nr.: HY-B0971AR
CAS. Nr.: 86-21-5
Synonyms: Prophenpyridamine (Standard); Tripoton (Standard); Pheniramine solution (Standard)
Forschungsgebiete:
Pheniramine (Standard) is the analytical standard of Pheniramine. This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .
Synonyms: Prophenpyridamine maleate (Standard); Tripoton maleate (Standard); Pheniramine maleate (Standard)
Forschungsgebiete:
Pheniramine (maleate) (Standard) is the analytical standard of Pheniramine (maleate). This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .
Art. -Nr.: HY-129105A
CAS. Nr.: 1867-58-9
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Forschungsgebiete:
Chlormethiazole (edisylate) is a sedative-hypnotic with active allosteric modulatory activity at GABAA receptors .
Art. -Nr.: HY-N8763
CAS. Nr.: 114912-36-6
Synonyms: Guaianin A
Category:
Tetracyclic Triterpenoids Terpenoids Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Araliaceae
Target:
Art. -Nr.: HY-163978
CAS. Nr.: 1350113-04-0
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Forschungsgebiete:
YGZ-331 is a sedative with a calming effect. YGZ-331 is a derivative of the adenosine nucleoside NGBA, which can increase GABA levels. YGZ-331 exerts a sedative-hypnotic effect by activating A1R and A2aR, and inhibiting CaMKII phosphorylation (pCaMKII) levels. YGZ-331 can reduce the spontaneous motor activity of mice .
Art. -Nr.: HY-108204
CAS. Nr.: 579494-66-9
Synonyms: THRX 918661
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Forschungsgebiete:
AZD 3043 (THRX 918661) is a positive allosteric modulator of GABA(A) receptors with sedative and hypnotic activity. AZD 3043 can enhance GABA(A) receptor-mediated chloride currents in vitro and produce hypnotic and electroencephalographic inhibitory effects in vivo. Due to its esterase-dependent metabolic pathway, it has a short duration of action and can be quickly cleared even after long-term infusion, which may have clinical application potential.
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Cloperidone acts as an inhibitor and substrate of CYP2C9, with an IC50 of 17.7 μM. Cloperidone exhibits enhanced cytotoxicity in cells expressing CYP2C9. It can be used in the research of sedative/hypnotic-related diseases .
Art. -Nr.: HY-119256
CAS. Nr.: 329221-34-3
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Forschungsgebiete:
COR627 is a GABA receptor positive allosteric modulator with the ability to enhance GABA activity. COR627 exhibits effects on GABA and baclofen stimulation in rat cortical membranes and can increase its affinity for GABA(B) receptors. In vivo experiments have shown that COR627 can enhance the sedative/hypnotic effects of baclofen at pretreatment ineffective doses .
Art. -Nr.: HY-103496
CAS. Nr.: 134516-99-7
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Forschungsgebiete:
U-90042 is a gamma-aminobutyric acidA receptor agonist of α1, α3 and α6 subtypes with Ki values of 7.8 nM, 9.5 nM and 11.0 nM, respectively. U-90042 suppresses locomotor activity and impairs rotarod performance in mice. U-90042 produces sedation and ataxia and prolongs sleeping time in mice, rats and monkeys. U-90042 can be used as a sedative and hypnotic agent .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
