541-46-8
Chemical Structure
Isovaleramide
Synonym(s): 3-Methylbutanamide
- CAS No.: 541-46-8
- Formula:C5H11NO
- Molecular Weight:101.15
IUPAC Name: 3-methylbutanamide
InChIKey: SANOUVWGPVYVAV-UHFFFAOYSA-N
SMILES: CC(C)CC(N)=O
Biological Activity: Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant. Isovaleramide inhibits alcohol dehydrogenase (ADH) activity and regulates GABAergic system. Isovaleramide reduces acute kidney injury. Isovaleramide has antiepileptic, anxiolytic, sedative and hypnotic effects[1][2][3][4].
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Isovaleramide | 98.0% | Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant. Isovaleramide inhibits alcohol dehydrogenase (ADH) activity and regulates GABAergic system. Isovaleramide reduces acute kidney injury. Isovaleramide has antiepileptic, anxiolytic, sedative and hypnotic effects. | ||||||||||||||||||||
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- [2]. Yang K, et al. Isovaleramide attenuates ethylene glycol poisoning‐induced acute kidney injury and reduces mortality by inhibiting alcohol dehydrogenase activity in rats[J]. Basic & Clinical Pharmacology & Toxicology, 2024.
- [3]. Park H J, et al. Studies on the components of valerian and isovaleramide[J]. YAKHAK HOEJI, 2010, 54(1): 1-7.
- [4]. Manavi M A. Exploring Valeriana species: Unraveling anticonvulsant potential through phytochemistry and pharmacology. Future Natural Products, 2024, 9(2): 100-110.
Keywords