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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
src-tyrosine
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "src-tyrosine" in MCE Product Catalog:
17
17 Cited Publications
Synonyms: src Kinase Inhibitor 1; src-l1
Src Inhibitor 1 is a potent, ATP-competitive and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.
PD166326 is an orally active tyrosine kinase inhibitor with a IC50 of 8 nM against abl tyrosine kinase and a IC50 of 6 nM against src tyrosine kinase. PD166326 blocks Bcr/Abl kinase activity. PD166326 inhibits Bcr/Abl-dependent proliferation and cell cycle progression. PD166326 reduces peripheral blood granulocytosis, alleviates splenomegaly and prolongs survival in a mouse model of chronic myeloid leukemia. PD166326 can be used in research related to chronic myeloid leukemia .
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PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively. PD-161570 inhibits PDGF-stimulated autophosphorylation and FGF-1 receptor phosphorylation with IC50s of 450 nM and 622 nM, respectively . PD-161570 is also a bone morphogenetic proteins (BMPs) and TGF-β signaling inhibitor .
PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC50s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC50=0.18 µM). PD-089828 also inhibits MAPK with an IC50 of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity .
Cat. No.: HY-P0200
CAS No.: 81156-93-6
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Cat. No.: HY-208739
CAS No.: 2569011-03-4
SRC tyrosine kinase IN-1 is a SRC inhibitor with an IC50 ranging from 1 μM to 10 μM. SRC tyrosine kinase IN-1 also acts as a YES1 inhibitor, with an IC50 of 1 μM to 10 μM. SRC tyrosine kinase IN-1 can be used in cancer research .
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Fenlean, a natural squamosamide derivative, is a Src tyrosine kinase inhibitor. Fenlean can inhibit over-activated microglia and protect dopaminergic neurons. Fenlean can attenuate neuroinflammation in Parkinson's disease models .
Cat. No.: HY-N14271
CAS No.: 151687-86-4
Synonyms: Angelmicin B
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Cat. No.: HY-N14273
CAS No.: 208588-83-4
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Cat. No.: HY-N14689
CAS No.: 208588-87-8
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Cat. No.: HY-N14267
CAS No.: 208588-76-5
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Cat. No.: HY-101053R
CAS No.: 179248-59-0
Synonyms: src Kinase Inhibitor 1 (Standard); src-l1 (Standard)
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Src Inhibitor 1 (Standard) is the analytical standard of Src Inhibitor 1 (HY-101053). This product is intended for research and analytical applications. Src Inhibitor 1 is a potent, ATP-competitive and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.
Cat. No.: HY-P85546
Synonyms: C src; C src kinase; C src tyrosine Kinase; C-src kinase; c-src tyrosine kinase; Csk A; CSK; CSK_HUMAN; CYTOPLASMIC tyrosine KINASE; MGC112926; MGC117393; MGC154049; P60 src; Protein tyrosine kinase CYL; Protein-tyrosine kinase CYL; Proto oncogene tyrosine protein kinase; tyrosine protein kinase CSK; tyrosine protein kinase CSK; tyrosine-protein kinase CSK; zgc:154049.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
