Hibarimicin B
Hibarimicin B (Angelmicin B) is a tyrosine kinase inhibitor. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL.
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- CAS No.: 151687-86-4
- 화학식: C85H112O37
- 분자량:1725.78
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Chemical Information
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CAS No. 151687-86-4
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분자량 1725.78
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화학식 C85H112O37
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SMILES
[H]C1([C@@](C2=C(C3=C(C(O)=C2C4=O)C(C(C(C(O)=C56)=C(OC)C(OC)=C6C=C7C[C@]8([C@H]([C@@H]([C@H]([C@](CCC)([C@](O)8C(C7=C5O)=O)O)O[C@H]9CC[C@@H]([C@H](O9)C)O[C@H]%10CC[C@@](C(C)=O)([C@@H](O%10)C)O)O)O[C@H]%11O[C@@H]([C@H]([C@H](C%11)O)O)C)[H])=C(C3=O)OC)=O)O)(O[C@]%12(CCC)[C@@]41O)[H])[C@@H](O[C@H]%13O[C@@H]([C@H]([C@H](C%13)O)O)C)[C@H](O)[C@H]%12O[C@H]%14CC[C@@H]([C@H](O%14)C)O[C@H]%15CC[C@@](C(C)=O)([C@@H](O%15)C)O
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Synonyms
Angelmicin B
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Structure Classification
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Initial Source
Microbispora rosea
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hibarimicin B Related Classifications
HY-N14271 Related Classifications
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