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Cat. No.: HY-N14271

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Hibarimicin B

(Synonyms: Angelmicin B)

Hibarimicin B (Angelmicin B) is a tyrosine kinase inhibitor. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL.

For research use only. We do not sell to patients.

CAS No.: 151687-86-4
Formula: C₈₅H₁₁₂O₃₇
Molecular Weight:1725.78

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Hibarimicin B Chemical Structure

CAS No.: 151687-86-4

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Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Src Isoforms :

Chemical Information

CAS No. 151687-86-4
Molecular Weight 1725.78
Formula C₈₅H₁₁₂O₃₇
SMILES

[H]C1([C@@](C2=C(C3=C(C(O)=C2C4=O)C(C(C(C(O)=C56)=C(OC)C(OC)=C6C=C7C[C@]8([C@H]([C@@H]([C@H]([C@](CCC)([C@](O)8C(C7=C5O)=O)O)O[C@H]9CC[C@@H]([C@H](O9)C)O[C@H]%10CC[C@@](C(C)=O)([C@@H](O%10)C)O)O)O[C@H]%11O[C@@H]([C@H]([C@H](C%11)O)O)C)[H])=C(C3=O)OC)=O)O)(O[C@]%12(CCC)[C@@]41O)[H])[C@@H](O[C@H]%13O[C@@H]([C@H]([C@H](C%13)O)O)C)[C@H](O)[C@H]%12O[C@H]%14CC[C@@H]([C@H](O%14)C)O[C@H]%15CC[C@@](C(C)=O)([C@@H](O%15)C)O
Synonyms

Angelmicin B
Structure Classification
- Quinones
- Naphthalene Quinones
Initial Source
- Microorganisms
Microbispora rosea
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sridhar Narayan, et al. Studies toward the total synthesis of angelmicin B (hibarimicin B): synthesis of a model CD-D' arylnaphthoquinone. Org Lett. 2004 Oct 14;6(21):3789-92. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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