Hibarimicin C
Hibarimicin C is a tyrosine kinase inhibitor. Hibarimicin C selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. Hibarimicin C also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 208588-83-4
- Formula: C83H110O36
- Molecular Weight:1683.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 208588-83-4
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Molecular Weight 1683.74
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Formula C83H110O36
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SMILES
CCCC12C3(C(C(C(C2O[C@@H]4O[C@@H]([C@H](CC4)O[C@@H]5O[C@@H]([C@H](CC5)O)C)C)O)O[C@H]6C[C@H]([C@H]([C@@H](O6)C)O)O)([H])C(C7=C(O)C(C(C(OC)=C(C8=C(C(OC)=C9C(C(O)=C%10C(CC%11([H])C(C%10=O)(C(O)(C(C(C%11O[C@H]%12C[C@H]([C@H]([C@@H](O%12)C)O)O)O)O[C@@H]%13O[C@@H]([C@H](CC%13)O[C@@H]%14O[C@H]([C@@](O)(CC%14)C(C)=O)C)C)CCC)O)=C9)=C8O)OC)C%15=O)=O)=C%15C(O)=C7C3=O)([H])O1)O
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Structure Classification
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Initial Source
Microbispora
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hibarimicin C Related Classifications
HY-N14273 Related Classifications
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