13 Results for "

substituted pyridine

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "substituted pyridine" in MCE Product Catalog:

Cat. No.: HY-32742
CAS No.: 128071-98-7
4-Bromo-2-fluoropyridine is a drug intermediate .
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Cat. No.: HY-W093017
CAS No.: 626-61-9
Research Areas:  

Others

4-Chloropyridine is a NNMT (Nicotinamide N-methyltransferase) substrate and suicide inhibition-based protein labeling scaffold precursor.4-Chloropyridine undergoes NNMT-catalyzed pyridine nitrogen methylation to increase C4 electrophilicity, enabling aromatic nucleophilic substitution by NNMT cysteine C159 for covalent NNMT modification and inactivation.4-Chloropyridine can be used for the research of various cancers .
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Cat. No.: HY-32748
CAS No.: 41404-58-4
Research Areas:  

Others

2-Bromo-5-fluoropyridine acts as a bromofluoropyridine starting material and an azaaryl halide coupling partner. 2-Bromo-5-fluoropyridine participates in an oxygen-promoted, ligand-free Pd (OAc)2-catalyzed Suzuki reaction, reacting with arylboronic acids to produce 5-fluoro-2-aryl-substituted pyridine derivatives. 2-Bromo-5-fluoropyridine can be used to synthesize 5-fluoro-2-(4-(methylsulfonyl) phenyl) pyridine, an intermediate of the GPR119 agonist GSK1292263A .
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Cat. No.: HY-34054
CAS No.: 4487-56-3
2,4-Dichloro-5-nitropyridine is a pyridine derivative, which can be used as a precursor to synthesize polyfluorinated pyrrolidine derivatives [3][4].
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Cat. No.: HY-W002718
CAS No.: 16063-69-7
Research Areas:  

Others

2,4,6-Trichloropyridine is a trichloro-substituted nitrogen-containing heterocyclic compound that serves as an intermediate for studies related to organic synthesis. 2,4,6-Trichloropyridine reacts with n-BuLi to form a stable 3-lithiated pyridine intermediate .
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Cat. No.: HY-W010023
CAS No.: 869557-43-7
Synonyms: 3-Bromo-5-fluoro-2-pyridinamine
2-Amino-3-bromo-5-fluoropyridine (3-Bromo-5-fluoro-2-pyridinamine) is a drug intermediate that can be used for the synthesis fluorinated pyridines .
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Cat. No.: HY-W001198
CAS No.: 16063-70-0
Research Areas:  

Others

2,3,5-Trichloropyridine is a trichloro-substituted pyridine derivative and also serves as an intermediate in the production of herbicidal active substances .
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Cat. No.: HY-121682
CAS No.: 61788-27-0
N-(2-Chlorophenyl)-1H-indole-3-carboxamide (Compound 60) is a substituted derivative of the pyrazolo[1,5-a]pyridine core. N-(2-Chlorophenyl)-1H-indole-3-carboxamide does not exhibit EphB3 kinase inhibitory activity and can be used as a negative control compound .
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Cat. No.: HY-203012
CAS No.: 2665712-31-0
Research Areas:  

Neurological Disease

NB-7 is a substituted pyridine derivative and SARM1 inhibitor. NB-7 can be used for the research of neurological disorders .
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Cat. No.: HY-117966
CAS No.: 145301-79-7
Target:  

mAChR

Research Areas:  

Cardiovascular Disease

Bibn 140 is a pyridine derivative substituted with a benzene ring, which has high affinity (Ki: 12 nM) and selectivity for M2 mAChR receptors over M1 receptors .
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Cat. No.: HY-U00287
CAS No.: 1254166-60-3
Target:  

Beta-secretase

Research Areas:  

Neurological Disease

BACE-IN-1 (Compound 13) is a substituted lmidazo[1 ,2-a]pyridine derivative which can inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer's disease.
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Cat. No.: HY-34005
CAS No.: 3743-22-4
Target:  

Glyoxalase (GLO)

Research Areas:  

Others

2-Dimethylaminophenol is an inhibitor of human glyoxalase 1 (GLO1). 2-Dimethylaminophenol disrupts metal binding by substituting the pyridine nitrogen donor with a dimethylamino group .
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Cat. No.: HY-W131404
CAS No.: 72648-80-7
Research Areas:  

Others

Boc-Aeg-OEt is an aminoethylglycine monomer based on a Boc- and ethyl ester-protected AEG backbone, with substitution by a pyridine ligand. Boc-Aeg-OEt reduces steric hindrance in a series of dipeptide synthesis reactions, and has higher solubility in common solvents than the Fmoc-aeg-OtBu backbone .
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