2,4,6-Trichloropyridine
Based on 1 Customer Validation
2,4,6-Trichloropyridine is a trichloro-substituted nitrogen-containing heterocyclic compound that serves as an intermediate for studies related to organic synthesis. 2,4,6-Trichloropyridine reacts with n-BuLi to form a stable 3-lithiated pyridine intermediate.
For research use only. We do not sell to patients.
- Purity: 99.98%
- CAS No.: 16063-69-7
- Formula: C5H2Cl3N
- Molecular Weight:182.44
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
2,4,6-trichloropyridine undergoes iterative ring-opening reaction with sulfonamide ester 1 via lithiation and catalysis by copper (I) iodide to produce dialkylated pyridine derivative 6[1].
2,4,6‑Trichloropyridine (TLP) is a nitrogen-containing heterocyclic compound with pharmacological activity and strong biological activity, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and reactive dyes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 16063-69-7
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Appearance <33°C Solid,>37°C Liquid
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Molecular Weight 182.44
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Formula C5H2Cl3N
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Color White to light yellow
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SMILES
ClC1=CC(Cl)=CC(Cl)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (548.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.4813 mL | 27.4063 mL | 54.8125 mL | 137.0314 mL |
| 5 mM | 1.0963 mL | 5.4813 mL | 10.9625 mL | 27.4063 mL | |
| 10 mM | 0.5481 mL | 2.7406 mL | 5.4813 mL | 13.7031 mL | |
| 15 mM | 0.3654 mL | 1.8271 mL | 3.6542 mL | 9.1354 mL | |
| 20 mM | 0.2741 mL | 1.3703 mL | 2.7406 mL | 6.8516 mL | |
| 25 mM | 0.2193 mL | 1.0963 mL | 2.1925 mL | 5.4813 mL | |
| 30 mM | 0.1827 mL | 0.9135 mL | 1.8271 mL | 4.5677 mL | |
| 40 mM | 0.1370 mL | 0.6852 mL | 1.3703 mL | 3.4258 mL | |
| 50 mM | 0.1096 mL | 0.5481 mL | 1.0963 mL | 2.7406 mL | |
| 60 mM | 0.0914 mL | 0.4568 mL | 0.9135 mL | 2.2839 mL | |
| 80 mM | 0.0685 mL | 0.3426 mL | 0.6852 mL | 1.7129 mL | |
| 100 mM | 0.0548 mL | 0.2741 mL | 0.5481 mL | 1.3703 mL |