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Art. -Nr.: HY-34005

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2-Dimethylaminophenol

Name: 2-Dimethylaminophenol
Brand: MedChemExpress
SKU: HY-34005
Price: 25.00 USD
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2-Dimethylaminophenol is an inhibitor of human glyoxalase 1 (GLO1). 2-Dimethylaminophenol disrupts metal binding by substituting the pyridine nitrogen donor with a dimethylamino group.

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CAS. Nr.: 3743-22-4
Formel: C₈H₁₁NO
Molecular Weight:137.18

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

2-Dimethylaminophenol Chemical Structure

CAS. Nr.: 3743-22-4

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
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Biologische Aktivität

Beschreibung

2-Dimethylaminophenol is an inhibitor of human glyoxalase 1 (GLO1). 2-Dimethylaminophenol disrupts metal binding by substituting the pyridine nitrogen donor with a dimethylamino group^[1].

In Vitro

2-Dimethylaminophenol (Compound 31) (200 μM; 30 min) shows no significant inhibitory effect on recombinant human MMP-2 at the concentration of 200 μM^[1].
2-Dimethylaminophenol (200 μM; 15-20 min) inhibits the activity of recombinant human GLO1 by 36% at a concentration of 200 μM^[1].
2-Dimethylaminophenol (200 μM; 15 min) exerts no significant inhibitory effect on recombinant human hCAII at the concentration of 200 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3743-22-4
Appearance Solid
Molecular Weight 137.18
Formel C₈H₁₁NO
SMILES

OC=1C=CC=CC1N(C)C
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Seo H, et al. Developing Metal-Binding Isosteres of 8-Hydroxyquinoline as Metalloenzyme Inhibitor Scaffolds. Inorg Chem. 2022;61(19):7631-7641. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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