2,4-Dichloro-5-nitropyridine
Based on 1 Customer Validation
2,4-Dichloro-5-nitropyridine is a pyridine derivative, which can be used as a precursor to synthesize polyfluorinated pyrrolidine derivatives[3][4].
For research use only. We do not sell to patients.
- Purity: 99.87%
- CAS No.: 4487-56-3
- Formula: C5H2Cl2N2O2
- Molecular Weight:192.99
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2,4-Dichloro-5-nitropyridine serves as a starting material for synthesis of SCD inhibitors[1].
2,4-Dichloro-5-nitropyridine acts as a starting material for regioselective synthesis of 3H-[1,2,3]triazolo[4,5-c]pyridine derivatives[2].
2,4-Dichloro-5-nitropyridine acts as a starting material for the kinase inhibitor BMS-986236[3].
2,4-Dichloro-5-nitropyridine acts as a starting material for TYK2 activator analogs[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4487-56-3
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Appearance Solid
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Molecular Weight 192.99
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Formula C5H2Cl2N2O2
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Color Light yellow to yellow
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SMILES
O=[N+](C1=CN=C(Cl)C=C1Cl)[O-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (518.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
[1]. Koltun DO, et al. Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitors. Bioorg Med Chem Lett. 2009;19(7):2048-2052. [Content Brief]
[2]. Marepu N, et al. 1,2,3-Triazole fused with pyridine/pyrimidine as new template for antimicrobial agents: Regioselective synthesis and identification of potent N-heteroarenes. Bioorg Med Chem Lett. 2018;28(20):3302-3306. [Content Brief]
[4]. Matsumoto H, et al. Identification of small molecule activators targeting TYK2 pseudokinase domain. Bioorg Med Chem Lett. 2025;123:130233. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1816 mL | 25.9081 mL | 51.8162 mL | 129.5404 mL |
| 5 mM | 1.0363 mL | 5.1816 mL | 10.3632 mL | 25.9081 mL | |
| 10 mM | 0.5182 mL | 2.5908 mL | 5.1816 mL | 12.9540 mL | |
| 15 mM | 0.3454 mL | 1.7272 mL | 3.4544 mL | 8.6360 mL | |
| 20 mM | 0.2591 mL | 1.2954 mL | 2.5908 mL | 6.4770 mL | |
| 25 mM | 0.2073 mL | 1.0363 mL | 2.0726 mL | 5.1816 mL | |
| 30 mM | 0.1727 mL | 0.8636 mL | 1.7272 mL | 4.3180 mL | |
| 40 mM | 0.1295 mL | 0.6477 mL | 1.2954 mL | 3.2385 mL | |
| 50 mM | 0.1036 mL | 0.5182 mL | 1.0363 mL | 2.5908 mL | |
| 60 mM | 0.0864 mL | 0.4318 mL | 0.8636 mL | 2.1590 mL | |
| 80 mM | 0.0648 mL | 0.3239 mL | 0.6477 mL | 1.6193 mL | |
| 100 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2954 mL |
2,4-Dichloro-5-nitropyridine Related Classifications
HY-34054 Related Classifications
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