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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
81 Results for "
tBu ester
" in MedChemExpress (MCE) Product Catalog:
Products (81)
81 Results for "tBu ester" in MCE Product Catalog:
1
1 Cited Publications
Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection .
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Cat. No.: HY-W007706
CAS No.: 71989-35-0
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Cat. No.: HY-W008016
CAS No.: 71989-38-3
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Cat. No.: HY-W007941
CAS No.: 71989-33-8
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DOTA-tris(tBu)ester NHS ester is a bifunctional precursor to a DOTA-based chelating agent. DOTA-tris(tBu)ester NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, and upon deprotection forms stable complexes with metal ions for applications in molecular imaging .
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2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine .
Cat. No.: HY-W614269
CAS No.: 306776-79-4
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DOTA-GA(tBu)4 stabilizes the attachment of radiometals to ligands. DOTA-GA(tBu)4 improves the biodistribution of radiolabeled second-generation Affibody molecules by increasing their net negative charge and reducing hepatic uptake, leading to enhanced tumor-to-blood and tumor-to-liver ratios. DOTA-GA(tBu)4 targets HER2>-expressing breast and gastrointestinal cancer .
Cat. No.: HY-W010964
CAS No.: 122996-47-8
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Cat. No.: HY-W008156
CAS No.: 128107-47-1
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Cat. No.: HY-W048700
CAS No.: 170643-02-4
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Cat. No.: HY-Y0912
CAS No.: 94790-37-1
Synonyms: N-HBTU
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HBTU (N-HBTU) is a guanidinium-based peptide coupling reagent and immunological sensitizer. HBTU can be used in combination with bases such as DIPEA (HY-130142) to complete coupling reactions, with HOBt and TMU as by-products. HBTU is a standard reagent in automated solid-phase peptide synthesis, particularly for the Fmoc/tBu strategy, which effectively promotes coupling steps, but it is not suitable for sterically hindered amino acids or dipeptide derivatives. HBTU can induce rhinitis, dermatitis, bronchial asthma and severe allergic reactions. HBTU can be used to study the pathogenesis of allergic reactions, occupational rhinitis, allergic contact dermatitis and bronchial asthma .
Cat. No.: HY-W011199
CAS No.: 47375-34-8
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Cat. No.: HY-W008426
CAS No.: 118488-18-9
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Cat. No.: HY-W250574
CAS No.: 1161415-28-6
Synonyms: NOTA-bis(t-Butyl ester)
Cat. No.: HY-W000843
CAS No.: 138797-71-4
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Cat. No.: HY-W013749
CAS No.: 197632-77-2
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Cat. No.: HY-W042013
CAS No.: 71989-43-0
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Cat. No.: HY-P2407
CAS No.: 1000164-43-1
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Cat. No.: HY-A0074
CAS No.: 174267-71-1
Synonyms: tetra-tBu-DTPA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
