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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
triplet
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "triplet" in MCE Product Catalog:
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1 Cited Publications
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2'-Deoxy-5-formylcytidine is an effective internal triplet photosensitizer in DNA. 2'-Deoxy-5-formylcytidine could act as a new hot spot in DNA photodamage .
Cat. No.: HY-W016618
CAS No.: 1603-79-8
Synonyms: Ethyl benzoylformate; Phenylglyoxylic acid ethyl ester
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Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
Cat. No.: HY-W017469
CAS No.: 487-68-3
Synonyms: 2,4,6-Trimethylbenzaldehyde
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Cat. No.: HY-W086988
CAS No.: 136-85-6
Synonyms: 5-Methylbenzotriazole
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5-Methyl-1H-benzotriazole (5-Methylbenzotriazole) is a benzotriazole derivative, and serves as a key building block for ultraviolet absorbers and light stabilizers. 5-Methyl-1H-benzotriazole reduces the photosensitizing ability of nitrate and dissolved organic matter (DOM), enhances the persistence of microorganic pollutants, inhibits the photodegradation of DOM and drug residues, and quenches the triplet excited states of DOM and methotrexate substructures. 5-Methyl-1H-benzotriazole acts as a corrosion inhibitor for copper and copper alloys, and is present in formulations of anti-icing fluids, dishwasher detergents, aircraft deicing fluids and automotive antifreezes .
Cat. No.: HY-W034043
CAS No.: 1335047-34-1
Thio-acridone (SACD) is a photosensitizer (HAF-PSs). Thio-acridone forms a long-lived triplet state upon excitation by 470 nm visible light,, ultimately generating singlet oxygen to damage the structures and functions of target cells such as cancer cells. Thio-acridone is promising for research of cancers . Thio-acridone is a CDK4/Cyclin D1 inhibitor (IC50 = 2 uM) .
Cat. No.: HY-W016618R
CAS No.: 1603-79-8
Synonyms: Ethyl benzoylformate (Standard); Phenylglyoxylic acid ethyl ester (Standard)
Research Areas:
Ethyl phenylglyoxylate (Ethyl benzoylformate) (Standard) is the analytical standard of Ethyl phenylglyoxylate (HY-W016618). This product is intended for research and analytical applications. Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
Cat. No.: HY-W701476
CAS No.: 1025892-26-5
Synonyms: Ethyl benzoylformate-d5; Phenylglyoxylic acid ethyl ester-d5
Cat. No.: HY-145538
CAS No.: 146877-98-7
Synonyms: 5'-Deoxyguanylic acid disodium hydrate
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2'-Deoxyguanosine 5'-monophosphate (5'-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism) .
Cat. No.: HY-118720A
CAS No.: 1638758-72-1
Synonyms: U-23 TFA
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Ovothiol A TFA (U-23 TFA) is an antioxidant. Ovothiol A TFA can be isolated from the tissues of marine invertebrates, algae and fish. Ovothiol A acts synergistically with glutathione to actively scavenge ROS and free radicals, and quench the triplet state of Kynurenic acid (HY-100806), thereby inhibiting oxidative stress and photodamage. OSH is expected to serve as an excellent photoprotective agent to inhibit the harmful effects caused by solar ultraviolet radiation .
Cat. No.: HY-W286414
CAS No.: 66840-71-9
Synonyms: DMST
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N,N-dimethyl-N'-p-tolylsulfamide (DMST) is a hydrolysis product of Tolylfluanid (HY-W774955). The photodegradation rate of N,N-dimethyl-N'-p-tolylsulfamide in coastal seawater is higher than that in seawater or deionized water .
Cat. No.: HY-W513043
CAS No.: 2679-01-8
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Methylene green is a cationic phenothiazine dye and a nitro derivative of Methylene blue (HY-14536), which exhibits a strong absorption band in the ~550-690 nm range. Methylene green supports photodynamic processes, cell staining, and biomolecule identification .
Cat. No.: HY-186211
CAS No.: 686720-00-3
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cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) is a photocatalytic prodrug of Cisplatin (HY-17394), which can be activated into the active Pt (II) form. In the presence of an electron donor, cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) undergoes a photocatalytic reduction reaction catalyzed by flavoproteins to produce Cisplatin. cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) can be used in cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
