cis,cis,trans-Diamminedichlorodisuccinatoplatinum(IV)
cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) is a photocatalytic prodrug of Cisplatin (HY-17394), which can be activated into the active Pt (II) form. In the presence of an electron donor, cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) undergoes a photocatalytic reduction reaction catalyzed by flavoproteins to produce Cisplatin. cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 686720-00-3
- Formula: C8H16Cl2N2O8Pt
- Molecular Weight:534.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) (500 μM) undergoes photoinduced photocatalytic conversion to cisplatin mediated by the mSOG flavoprotein variant, achieving 100% substrate conversion within 5 min[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 686720-00-3
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Molecular Weight 534.21
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Formula C8H16Cl2N2O8Pt
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SMILES
O=C(CCC([O-][Pt+4]([Cl-])([O-]C(CCC(O)=O)=O)([NH3])([NH3])[Cl-])=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)