686720-00-3
686720-00-3
Chemical Structure
cis,cis,trans-Diamminedichlorodisuccinatoplatinum(IV)
- CAS No.: 686720-00-3
- Formula:C8H16Cl2N2O8Pt
- Molecular Weight:534.21
InChIKey: PJHPRYNSXRQBMS-UHFFFAOYSA-J
SMILES: O=C(CCC([O-][Pt+4]([Cl-])([O-]C(CCC(O)=O)=O)([NH3])([NH3])[Cl-])=O)O
Biological Activity: cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) is a photocatalytic prodrug of Cisplatin (HY-17394), which can be activated into the active Pt (II) form. In the presence of an electron donor, cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) undergoes a photocatalytic reduction reaction catalyzed by flavoproteins to produce Cisplatin. cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) can be used in cancer research[1].
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cis,cis,trans-Diamminedichlorodisuccinatoplatinum(IV) | cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) is a photocatalytic prodrug of Cisplatin (HY-17394), which can be activated into the active Pt (II) form. In the presence of an electron donor, cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) undergoes a photocatalytic reduction reaction catalyzed by flavoproteins to produce Cisplatin. cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) can be used in cancer research. | |||||||||||||||||||||
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References
