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Sucrose octaacetate 

Cat. No.: HY-119309 Purity: >98.0%
Handling Instructions

Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers.

For research use only. We do not sell to patients.

Sucrose octaacetate Chemical Structure

Sucrose octaacetate Chemical Structure

CAS No. : 126-14-7

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10 mM * 1  mL in DMSO USD 55 In-stock
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100 mg USD 50 In-stock
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Description

Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers[1][2][3].

In Vitro

Sucrose octaacetate is nontoxic and has a number of uses based on its bitter taste. For example, sugar is rendered too bitter is eat at a concentration of 0.06% (w/w) Sucrose octaacetate. Sucrose octaacetate can form 255 different possible isomers and degradation products, all of which have a very low molar absorptivity[1].
Polyaniline (PANI) nanofibers and nanorods are obtained using 2 and 3 g Sucrose octaacetate, respectively. The nanostructures containing irregular-shaped agglomerates, such as particulate particles and scaffolds are observed with increasing the concentrations of Sucrose octaacetate. The presence of Sucrose octaacetate during polymerization could only induce a change in morphology, but could not influence the molecular structure of the resulting PANI. Compared with those derived with 1, 3, and 4 g Sucrose octaacetate, the polymerized PANI from 2 g Sucrose octaacetate possesses higher thermal stability and electrical conductivity due to its higher crystallinity and highly ordered structure[3].

In Vivo

No recombination has been found between Sucrose octaacetate-avoidance phenotype and PRP haplotype in any mouse population. Soa and Prp, therefore, are either very near each other or identical. To assess the latter possibility, two type-A, proline-rich protein genes (MP2 and M14), situated approximately 30 kb apart at the Prp locus, are separately transferred from a Sucrose octaacetate-taster inbred strain (SWR) to a Sucrose octaacetate-nontaster inbred strain (FVB). Five MP2-transgenic mice and seven M14-transgenic mice are insensitive to 1 mM Sucrose octaacetate in two-bottle tests, thus retaining the nontaster FVB phenotype. Expression of mRNAs for both type-A Prp genes alone or together do not enhance SOA taste sensitivity in nontaster mice[2].

Molecular Weight

678.59

Formula

C₂₈H₃₈O₁₉

CAS No.

126-14-7

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (368.41 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4736 mL 7.3682 mL 14.7364 mL
5 mM 0.2947 mL 1.4736 mL 2.9473 mL
10 mM 0.1474 mL 0.7368 mL 1.4736 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (3.07 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (3.07 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.07 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

Sucrose octaacetateOthersBitterfoodadditiveadhesiveplasticizerpesticidesinsecticidespolyanilinesofttemplateInhibitorinhibitorinhibit

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Sucrose octaacetate
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HY-119309
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