Stachyose hydrate
Based on 1 publication(s) in Google Scholar
Stachyose hydrate is an orally active prebiotic that enhances the growth and activity of beneficial bacteria. Stachyose hydrate has hypoglycemic effects and can improve inflammation by regulating gut microbiota. In addition, Stachyose hydrate can induce plant cell apoptosis (Apoptosis). Stachyose hydrate can be used in research on inflammation, gastrointestinal diseases, and agriculture .
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 54261-98-2
- Formula: C24H42O21.xH2O
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Stachyose hydrate
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Stachyose hydrate (3.2 mg/mL, 36 h, 48 h) induces apoptotic-like programmed cell death in Nicotiana benthamiana leaf cells, characterized by nuclear DNA fragmentation[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Nicotiana benthamiana leaf cells (tobacco, plant)
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Concentration:3.2 mg/mL
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Incubation Time:36 h, 48 h
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Result:Resulted in nuclear DNA fragmentation. Induced apoptotic-like programmed cell death.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:DSS (HY-116282C)-induced ulcerative colitis C57BL/6J mouse model[2]
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Dosage:200, 400, 600 mg/kg
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Administration:Oral gavage (p.o.), once daily for 3 weeks
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Result:Significantly alleviated colitis symptoms in DSS-induced colitis mice, including reducing weight loss, lowering disease activity index (DAI), and increasing colon length, while restoring colonic epithelial barrier integrity. Dose-dependently upregulated mRNA expression of ZO-1, Claudin-1, and Occludin, reduced IL-17, TNF-α, IL-1β, and IL-6 expression, and increased IL-10 levels.
Chemical Information
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CAS No. 54261-98-2
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Appearance Solid
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Formula C24H42O21.xH2O
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Color White to off-white
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SMILES
OC[C@@](O[C@@H]1CO)([C@H]([C@@H]1O)O)O[C@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)CO[C@H]([C@@H]([C@H]3O)O)O[C@@H]([C@@H]3O)CO[C@H]([C@@H]([C@H]4O)O)O[C@@H]([C@@H]4O)CO.[x H2O]
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Food Sci Nutr
Screening Based on Structural and Biological Verification of Stachyose as a PPARγ-Modulating Ligand for the Treatment of Non-Alcoholic Fatty Liver Disease. [Abstract]2025 Sep 22;13(9):e71009. PMID: 40994455
Solvent & Solubility
H2O : 125 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Cai-Na Li, et al. Berberine combined with stachyose induces better glycometabolism than berberine alone through modulating gut microbiota and fecal metabolomics in diabetic mice. Phytother Res. 2020 May;34(5):1166-1174. [Content Brief]
[2]. He N, et al. Stachyose Exerts Anticolitis Efficacy by Re-balancing Treg/Th17 and Activating the Butyrate-Derived PPARγ Signaling Pathway. J Agric Food Chem. 2024 May 29;72(21):12171-12183. [Content Brief]
[3]. Okemo P, et al. Stachyose triggers apoptotic like cell death in drought sensitive but not resilient plants. Sci Rep. 2021 Mar 29;11(1):7099. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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