2. Vitamin D Related/Nuclear Receptor
    Metabolic Enzyme/Protease
  3. VD/VDR
    Endogenous Metabolite
  4. Tachysterol 3

Tachysterol 3 

Cat. No.: HY-130705A Purity: 98.19%
COA Handling Instructions

Tachysterol 3 is a photoproduct of Previtamin D3 (HY-130705).

For research use only. We do not sell to patients.

Tachysterol 3 Chemical Structure

Tachysterol 3 Chemical Structure

CAS No. : 17592-07-3

Size Price Stock Quantity
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 650 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1450 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2400 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3900 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Tachysterol 3:

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Tachysterol 3 is a photoproduct of Previtamin D3 (HY-130705)[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Tachysterol 3 can be hydroxylated by CYP11A1 and CYP27A1[2].
Tachysterol 3 is detected in human serum at a concentration of 7.3 ± 2.5 ng/mL[2].
Tachysterol 3 hydroxyderivatives show high-affinity binding to the ligan-binding domain (LBD) of the liver X receptor (LXR) α and β, and the peroxisome proliferator-activated receptor γ (PPARγ) in LanthaScreen TR-FRET coactivator assays[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

384.64

Appearance

Oil

Formula

C27H44O
CAS No.
SMILES

O[[email protected]@H]1CC(/C=C/C2=CCC[[email protected]]3(C)[[email protected]@H]([[email protected]](C)CCCC(C)C)CC[[email protected]@]23[H])=C(C)CC1
Shipping

Shipping with dry ice.
Storage

-80°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
In Vitro: 

DMSO : 130 mg/mL (337.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5998 mL 12.9992 mL 25.9983 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL
10 mM 0.2600 mL 1.2999 mL 2.5998 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 3.25 mg/mL (8.45 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3.25 mg/mL (8.45 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3.25 mg/mL (8.45 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 98.19%

COA (246 KB) RP-HPLC (220 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Tachysterol 317592-07-3Tachysterol3Tachysterol-3VD/VDREndogenous MetaboliteVitamin DVitamin D receptorvitamin Dprevitamin D3CYP11A1CYP27A1human serumInhibitorinhibitorinhibit

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