1. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  2. VD/VDR Endogenous Metabolite
  3. Tachysterol 3

Tachysterol 3 is a photoproduct of Previtamin D3 (HY-130705).

For research use only. We do not sell to patients.

Tachysterol 3 Chemical Structure

Tachysterol 3 Chemical Structure

CAS No. : 17592-07-3

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Based on 1 publication(s) in Google Scholar

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Description

Tachysterol 3 is a photoproduct of Previtamin D3 (HY-130705)[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Tachysterol 3 can be hydroxylated by CYP11A1 and CYP27A1[2].
Tachysterol 3 is detected in human serum at a concentration of 7.3 ± 2.5 ng/mL[2].
Tachysterol 3 hydroxyderivatives show high-affinity binding to the ligan-binding domain (LBD) of the liver X receptor (LXR) α and β, and the peroxisome proliferator-activated receptor γ (PPARγ) in LanthaScreen TR-FRET coactivator assays[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

384.64

Formula

C27H44O

CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

O[C@@H]1CC(/C=C/C2=CCC[C@]3(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@]23[H])=C(C)CC1

Structure Classification
Initial Source
Shipping

Shipping with dry ice.

Storage

-80°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Purity & Documentation

Purity: 99.68%

References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tachysterol 3
Cat. No.:
HY-130705A
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