31 Results for "

PRX

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "PRX" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P71147
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDX3; Protein MER5 Homolog; Prev. AOP1; PRX-III; AOP-1; HBC189; Thioredoxin-Dependent Peroxide Reductase, Mitochondrial; Epididymis Secretory Sperm Binding Protein; Thioredoxin-Dependent Peroxiredoxin 3; Peroxiredoxin-3; Antioxidant Protein 1; PRO1748; S
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1
1 Cited Publications
Cat. No.: HY-P71232
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDX4; Peroxiredoxin-4; Peroxiredoxin 4; PRX-IV; AOE37-2; Epididymis Secretory Sperm Binding Protein Li 97n; Thioredoxin-Dependent Peroxide Reductase A0372; Thioredoxin Peroxidase (Antioxidant Enzyme); Thioredoxin-Dependent Peroxiredoxin 4; Thioredoxin-De
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Cat. No.: HY-P99405
CAS No.: 1960462-19-4
Synonyms: PRX 002; RG 7935; RO 7046015

Target:  

α-synuclein

Research Areas:  

Neurological Disease

Prasinezumab (PRX 002) is a humanized IgG1 monoclonal antibody directed against aggregated α-synuclein. Prasinezumab has the potential for Parkinson's disease research .
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Cat. No.: HY-15472
CAS No.: 866206-54-4
Purity:  97.46%
PRX-08066 is a selective and orally active 5-hydroxytryptamine receptor 2B (5-HT2BR) antagonist with a Ki of 3.4 nM. PRX-08066 inhibits the MAPK pathway, 5-HT release and fibrotic factor (TGFβ1, CTGF and FGF2) expression. PRX-08066 inhibits the proliferation of KRJ-I cells and induces apoptosis (caspase-3 activation). PRX-08066 inhibits pulmonary vascular remodeling. PRX-08066 can be used of pulmonary Arterial Hypertension (PAH) and neuroendocrine tumor (NET) .
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Cat. No.: HY-P99658
CAS No.: 2014343-04-3
Synonyms: PRX-003
Imaprelimab is a humanized IgG1κ anti-CD146 antibody. Imaprelimab exerts anti-angiogenic effects on brain metastasis of lung cancer in animal models. Imaprelimab can be used in studies related to brain metastasis of non-small cell lung cancer .
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Cat. No.: HY-P991704
CAS No.: 3031519-40-8
Synonyms: PRX-005

Target:  

Tau Protein

Research Areas:  

Neurological Disease

Moponetug (PRX-005), an anti-microtubule binding region (MTBR) tau monoclonal antibody, is a humanized monoclonal tri-epitopic antibody. Moponetug binds with high affinity to the R1, R2, and R3 repeats in the MTBR region of tau, and targets both 3R and 4R tau isoforms. Moponetug can be used for the study of Alzheimer’s disease .
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Cat. No.: HY-14559
CAS No.: 903580-39-2
Purity:  98.97%
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a Ki= 4-8 nM and an IC50 of 19 nM. PRX-07034 can be used for the research of enhancing working memory and cognitive flexibility .
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Cat. No.: HY-100171
CAS No.: 639029-42-8
Synonyms: GW876167 hydrochloride; BVT-933 hydrochloride
Target:  

5-HT Receptor

Research Areas:  

Cardiovascular Disease

PRX933 hydrochloride is a 5-HT2c receptor agonist extracted from patent WO 2014140631 A1.
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Cat. No.: HY-14848
CAS No.: 740873-06-7
Purity:  98.05%
Synonyms: PRX 00023
Research Areas:  

Neurological Disease

Naluzotan is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K + channel blocker, with IC50 of 3800 nM.
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Cat. No.: HY-158198
CAS No.: 2396759-31-0
PRXS571 is a potent modulator of the neuronal integrated stress response (ISR) and can be used in neural-related research .
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Cat. No.: HY-P99543
CAS No.: 1623177-41-2
Synonyms: OPRX-106; PRX-106; TNFR-Fc

Target:  

TNF Receptor

Research Areas:  

Cancer

Tulinercept (OPRX-106) is a recombinant TNF receptor fusion protein fused to an IgG1 Fc domain .
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Cat. No.: HY-15472A
CAS No.: 866206-55-5
PRX-08066 maleate is a selective and orally active 5-hydroxytryptamine receptor 2B (5-HT2BR) antagonist with a Ki of 3.4 nM. PRX-08066 maleate inhibits the MAPK pathway, 5-HT release and fibrotic factor (TGFβ1, CTGF and FGF2) expression. PRX-08066 maleate inhibits the proliferation of KRJ-I cells and induces apoptosis (caspase-3 activation). PRX-08066 maleate inhibits pulmonary vascular remodeling. PRX-08066 maleate can be used of pulmonary Arterial Hypertension (PAH) and neuroendocrine tumor (NET) .
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Cat. No.: HY-W671129
CAS No.: 68930-68-7
Frenolicin B is a covalent enzyme inhibitor and an orally active antiparasitic agent, with an IC50 of 0.2 μM against human Prx1. Frenolicin B selectively inhibits Glutaredoxin 3 via covalent modification of the active-site cysteines Cys159/Cys261. Frenolicin B selectively inhibits Peroxiredoxin 1 via covalent modification of the active-site cysteines Cys83/Cys173. Frenolicin B can be used in research related to colon cancer, breast cancer, lung cancer and malaria .
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Cat. No.: HY-19846
CAS No.: 869493-26-5
Synonyms: PRX-03140 potassium salt
Target:  

5-HT Receptor

Research Areas:  

Others

VRX-03011 (PRX-03140 (potassium salt)) is a compound with the potential to enhance memory and regulate acetylcholine release. It is a 5-HT? agonist that can enhance memory, regulate hippocampal acetylcholine efflux, and regulate APP metabolism without gastrointestinal side effects.
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Cat. No.: HY-RS11265
Research Areas:  

Others

PRX Human Pre-designed siRNA Set A contains three designed siRNAs for PRX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17938
Research Areas:  

Others

Prx Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prx gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24409
Research Areas:  

Others

Prx Rat Pre-designed siRNA Set A contains three designed siRNAs for Prx gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-100171A
CAS No.: 313658-33-2
Synonyms: BVT-933
Target:  

5-HT Receptor

Research Areas:  

Metabolic Disease

PRX933 (BVT-933) is a 5-HT2C agonist that can be used in the study of obesity and glaucoma.
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Cat. No.: HY-14848A
CAS No.: 740873-82-9
Purity:  99.63%
Synonyms: PRX 00023 hydrochloride
Research Areas:  

Neurological Disease

Naluzotan hydrochloride is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K + channel blocker, with IC50 of 3800 nM.
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Cat. No.: HY-RS11079
Research Areas:  

Others

PRDX6 Human Pre-designed siRNA Set A contains three designed siRNAs for PRDX6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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