2014343-04-3
2014343-04-3
Chemical Structure
Imaprelimab
Synonym(s): PRX-003
- CAS No.: 2014343-04-3
- Formula:N/A
- Molecular Weight:(144.74 kDa)
SMILES: [Imaprelimab]
Biological Activity: Imaprelimab is a humanized IgG1κ anti-CD146 antibody. Imaprelimab exerts anti-angiogenic effects on brain metastasis of lung cancer in animal models. Imaprelimab can be used in studies related to brain metastasis of non-small cell lung cancer[1][2].
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Imaprelimab | ≥99.0% | Imaprelimab is a humanized IgG1κ anti-CD146 antibody. Imaprelimab exerts anti-angiogenic effects on brain metastasis of lung cancer in animal models. Imaprelimab can be used in studies related to brain metastasis of non-small cell lung cancer. | ||||||||||||||||||||
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References
- [1]. Liu W, et al. CD146+ pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis. Theranostics. 2026;16(4):1905-1924. Published 2026 Jan 1. [Content Brief]
- [2]. Pelletier J P R, et al. Passive monoclonal and polyclonal antibody therapies[M]//Immunologic concepts in transfusion medicine. Elsevier, 2020: 251-348.
