PRDX3 Protein, Human

The PRDX3 protein is a thiol-specific peroxidase that plays a key role in cellular defense by reducing hydrogen peroxide and organic hydroperoxides to water and alcohols. It detoxifies peroxides and cooperates with MAP3K13 to regulate NF-kappa-B activation. PRDX3 Protein, Human is the recombinant human-derived PRDX3 protein, expressed by E. coli , with tag free. The total length of PRDX3 Protein, Human is 194 a.a., with molecular weight of ~25.0 kDa.

PRDX3, a thiol-specific peroxidase, serves as a pivotal catalyst in the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. This enzymatic activity plays a crucial role in cellular defense against oxidative stress by detoxifying peroxides. In addition to its role as a peroxidase, PRDX3 collaborates synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. This multifunctional protein is not only integral to the cellular defense against oxidative damage but also contributes to the maintenance of physical strength, emphasizing its significance in cellular homeostasis and stress response pathways.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

Tag Free

P30048 (P63-Q256)

10935  [NCBI]

PAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ

Approximately 25.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Solution

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.