740873-82-9
740873-82-9
Chemical Structure
Naluzotan hydrochloride
Synonym(s): PRX 00023 hydrochloride
- CAS No.: 740873-82-9
- Formula:C23H39ClN4O3S
- Molecular Weight:487.10
InChIKey: QBACIVGQRFVOBZ-UHFFFAOYSA-N
SMILES: CC(NC1=CC=CC(N2CCN(CCCCNS(=O)(CC3CCCCC3)=O)CC2)=C1)=O.Cl
Biological Activity: Naluzotan hydrochloride is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K+ channel blocker, with IC50 of 3800 nM.
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Naluzotan hydrochloride | 99.63% | Naluzotan hydrochloride is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K+ channel blocker, with IC50 of 3800 nM. | ||||||||||||||||||||
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Keywords
