740873-06-7
740873-06-7
Chemical Structure
Naluzotan
Synonym(s): PRX 00023
- CAS No.: 740873-06-7
- Formula:C23H38N4O3S
- Molecular Weight:450.64
IUPAC Name: N-(3-(4-(4-((cyclohexylmethyl)sulfonamido)butyl)piperazin-1-yl)phenyl)acetamide
InChIKey: SPWZXWDPAWDKQE-UHFFFAOYSA-N
SMILES: CC(NC1=CC=CC(N2CCN(CCCCNS(=O)(CC3CCCCC3)=O)CC2)=C1)=O
Biological Activity: Naluzotan is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K+ channel blocker, with IC50 of 3800 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Naluzotan | 98.05% | Naluzotan is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K+ channel blocker, with IC50 of 3800 nM. | ||||||||||||||||||||
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