1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. 4-Aminopyridine

4-Aminopyridine (Synonyms: 4-AP; 4-Pyridinamine; Fampridine)

Cat. No.: HY-B0604 Purity: 99.97%
Handling Instructions

4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.

For research use only. We do not sell to patients.

4-Aminopyridine Chemical Structure

4-Aminopyridine Chemical Structure

CAS No. : 504-24-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 84 In-stock
Estimated Time of Arrival: December 31
5 g USD 76 In-stock
Estimated Time of Arrival: December 31
10 g USD 115 In-stock
Estimated Time of Arrival: December 31
50 g   Get quote  

* Please select Quantity before adding items.

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Description

4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (531.29 mM)

H2O : 50 mg/mL (531.29 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.6259 mL 53.1293 mL 106.2586 mL
5 mM 2.1252 mL 10.6259 mL 21.2517 mL
10 mM 1.0626 mL 5.3129 mL 10.6259 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (26.56 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (26.56 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (26.56 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

94.11

Formula

C₅H₆N₂

CAS No.

504-24-5

SMILES

NC1=CC=NC=C1

Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.97%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
4-Aminopyridine
Cat. No.:
HY-B0604
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4-Aminopyridine

Cat. No.: HY-B0604