23 Results for "

4-aminopyridine

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "4-aminopyridine" in MCE Product Catalog:

4
CCZ01048 TFA
CCZ01048 TFA
0 Images
4 Cited Publications
Cat. No.: HY-P2336A
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
1
Didemnin B
Didemnin B
0 Images
1 Cited Publications
Cat. No.: HY-105055
CAS No.: 77327-05-0
Purity:  99.95%
Category:  

Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer

Target:  

Others

Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
Insulin icodec
Insulin icodec
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Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
NODAGA-LM3
NODAGA-LM3
0 Images
Cat. No.: HY-P5362
Target:  

Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor

Research Areas:  

Neurological Disease Cancer

NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
3-Hydroxy-4-aminopyridine
3-Hydroxy-4-aminopyridine
0 Images
Cat. No.: HY-W008188
CAS No.: 52334-53-9
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

3-Hydroxy-4-aminopyridine is an endogenous metabolite.
ZP3022
ZP3022
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Cat. No.: HY-P10341
CAS No.: 1345835-12-2
Target:  

GCGR

Research Areas:  

Metabolic Disease

ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
3-Hydroxy-4-aminopyridine (Standard)
3-Hydroxy-4-aminopyridine (Standard)
0 Images
Cat. No.: HY-W008188R
CAS No.: 52334-53-9
Category:  

Natural Products Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

3-Hydroxy-4-aminopyridine is an endogenous metabolite.
Nerispirdine
Nerispirdine
0 Images
Cat. No.: HY-106017
CAS No.: 119229-65-1
Target:  

Potassium Channel Sodium Channel

Research Areas:  

Neurological Disease

Nerispirdine is an ion channel inhibitor with IC50s of 3.6, 3.7 and 11.9 μM against K(v)1.1, K(v)1.2 and voltage-dependent Na(+) channel, respectively. Nerispirdine is a 4-aminopyridine (4-AP, HY-B0604) derivative and can be utilized in research on neurological disorders .
A3-APO
A3-APO
0 Images
Cat. No.: HY-P11004
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
Azaline B
Azaline B
0 Images
Cat. No.: HY-P10472
CAS No.: 134457-28-6
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
N1-Glutathionyl-spermidine disulfide
N1-Glutathionyl-spermidine disulfide
0 Images
Cat. No.: HY-P4757
CAS No.: 108081-77-2
Target:  

Parasite

Research Areas:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
RuBi-4AP
RuBi-4AP
0 Images
Cat. No.: HY-108578
CAS No.: 851956-02-0
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

RuBi-4AP, a derivative of 4-aminopyridine (4AP; HY-B0604), is a caged Kv channel blocker. RuBi-4AP contains a photolabile protecting group, allowing its effect to be controlled precisely in both space and time with light. RuBi-4AP can be used for the research of neuronal excitability, synaptic transmission, and signal propagation .
EphA4 agonist compound 23
EphA4 agonist compound 23
0 Images
Cat. No.: HY-P11243
Target:  

Ephrin Receptor

Research Areas:  

Neurological Disease

EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases .
AP102
AP102
0 Images
Cat. No.: HY-P2434
CAS No.: 846569-60-6
Target:  

Somatostatin Receptor

Research Areas:  

Neurological Disease Metabolic Disease Cancer

AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
NODAGA-LM3 TFA
NODAGA-LM3 TFA
0 Images
Cat. No.: HY-P5362A
Target:  

Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor

Research Areas:  

Cancer

NODAGA-LM3 TFA is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 TFA does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 TFA shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 TFA can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
TAK 044
TAK 044
0 Images
Cat. No.: HY-105168
CAS No.: 157380-72-8
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
4-Aminopyridine-2,6-dicarboxylic acid
4-Aminopyridine-2,6-dicarboxylic acid
0 Images
Cat. No.: HY-W273015
CAS No.: 2683-49-0
Synonyms: 4-aminopyridine-2,6-dicarboxylic hydrochloride salt
Target:  

MOFs

Research Areas:  

Others

4-Aminopyridine-2,6-dicarboxylic acid (4-AMinopyridine-2,6-dicarboxylic hydrochloride salt) is a metal-organic framework (MOF).
4,4'-4-Aminopyridine-3,5-diyldibenzoic acid
4,4'-4-Aminopyridine-3,5-diyldibenzoic acid
0 Images
Cat. No.: HY-W112438
CAS No.: 2396569-97-2
Target:  

MOFs

Research Areas:  

Others

4,4'-(4-Aminopyridine-3,5-diyl)dibenzoic acid is a metal-organic framework (MOF).
EMD 55068
EMD 55068
0 Images
Cat. No.: HY-P2075
CAS No.: 126784-34-7
Target:  

Renin

Research Areas:  

Endocrinology

EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
mcK6A1
mcK6A1
0 Images
Cat. No.: HY-P10876
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
Assay Types