14 Results for "

5(6)-Carboxyfluorescein

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "5(6)-Carboxyfluorescein" in MCE Product Catalog:

119
CFDA-SE
CFDA-SE
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119 Publications Verification
Cat. No.: HY-D0938
CAS No.: 150347-59-4
Synonyms: CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester
CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
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6
5(6)-CFDA
5(6)-CFDA
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6 Cited Publications
Cat. No.: HY-D0722
CAS No.: 124387-19-5
Synonyms: 5-(6)-Carboxyfluorescein diacetate; CFDA
5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
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5
5(6)-Carboxyfluorescein
5(6)-Carboxyfluorescein
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5 Cited Publications
Cat. No.: HY-15940
CAS No.: 72088-94-9
Synonyms: 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
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4
5(6)-FAM SE
5(6)-FAM SE
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4 Cited Publications
Cat. No.: HY-15937
CAS No.: 117548-22-8
Synonyms: 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester; 5(6)-Carboxyfluorescein succinimidyl ester mixed isomers
5(6)-FAM SE is a green fluorescent dye widely used for protein labeling.
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3
BCECF
BCECF
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3 Cited Publications
Cat. No.: HY-101882
CAS No.: 85138-49-4
Pureté:  ≥94.0%
Synonyms: 2′,7′-Bis(2-carboxyethyl)-5(6)-Carboxyfluorescein
BCECF is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
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Semaglutide-d8
Semaglutide-d8
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Cat. No.: HY-114118S
Target:  

Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family

Domaines de recherche:  

Neurological Disease Metabolic Disease Cancer

Semaglutide-d8 is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
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Semaglutide-d8 tetraTFA
Semaglutide-d8 tetraTFA
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Cat. No.: HY-114118S1
Target:  

Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family

Domaines de recherche:  

Neurological Disease Metabolic Disease Cancer

Semaglutide-d8 tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
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​JOE
​JOE
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Cat. No.: HY-D1090
CAS No.: 82855-40-1
JOE is a xanthene fluorophore (i.e., 4′,5′-dichloro-2′,7′-dimethoxy-5 (6)-carboxyfluorescein; 2',7'-dimethoxy-4',5'-dichloro-6-carboxyfluorescein) with an absorption wavelength of approximately 525 nm and an emission wavelength of approximately 550 nm. The fluorescence quantum yield of JOE correlates with the rigidity of the linker arm and the distance to dG nucleoside. JOE is commonly used as a fluorescent label for oligonucleotides and molecular beacon probes, and also serves as the acceptor fluorophore in fluorescence energy transfer primers for DNA sequencing .
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TAT (47-57), FAM-labeled acetate
TAT (47-57), FAM-labeled acetate
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Cat. No.: HY-P4122A
Target:  

HIV

Domaines de recherche:  

Others

TAT (47-57), FAM-labeled acetate is a 5(6)-Carboxyfluorescein (HY-15940)-labeled TAT (HY-P0281). TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide .
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TAT (47-57), FAM-labeled
TAT (47-57), FAM-labeled
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Cat. No.: HY-P4122
CAS No.: 1676104-81-6
Target:  

HIV

Domaines de recherche:  

Others

TAT (47-57), FAM-labeled is a 5(6)-Carboxyfluorescein (HY-15940)-labeled TAT (HY-P0281). TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide .
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5(6)-Carboxyfluorescein diisobutyrate
5(6)-Carboxyfluorescein diisobutyrate
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Cat. No.: HY-D1477
CAS No.: 287111-44-8
5(6)-Carboxyfluorescein diisobutyrate is a protected 5(6)-carboxyfluorescein. 5(6)-carboxyfluorescein is a fluorescence pH indicator .
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5-Carboxyrhodamine 110 NHS ester
5-Carboxyrhodamine 110 NHS ester
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Cat. No.: HY-D2773
CAS No.: 219729-26-7
5-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS Ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. For many applications, the dye is preferred over 5-(6)-carboxyfluorescein NHS ester or FITC because of its exceptional photostability and fluorescence insensitivity to pH (4-9). Although the mixed isomers of Carboxyrhodamine 110 NHS Ester preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.
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Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone
Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone
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Cat. No.: HY-P4901
CAS No.: 1926163-69-0
Target:  

Amino Acid Derivatives

Domaines de recherche:  

Others

Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone is a polypeptide.
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BCECF (solution)
BCECF (solution)
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Cat. No.: HY-DY1098
CAS No.: 85138-49-4
Synonyms: 2′,7′-Bis(2-carboxyethyl)-5(6)-Carboxyfluorescein (solution)
BCECF (solution) (2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein (solution)) is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
Solvent and concentration: DMSO: 10 mM
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