Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
Avermectin B1
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "Avermectin B1" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: Abamectin; Avermectin B1a-Avermectin B1b mixt.
2
Research Areas:
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .
1
Target:
Research Areas:
Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
1
1 Cited Publications
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) . Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
Cat. No.: HY-15311R
CAS No.: 71751-41-2
Synonyms: Abamectin (Standard); Avermectin B1a-Avermectin B1b mixt. (Standard)
Cat. No.: HY-W765152
CAS No.: 2962875-16-5
Synonyms: 22,23-Dihydro Avermectin B1a; epi-Dihydro Avermectin B1a
epi-Ivermectin B1a is a key related substance of Ivermectin (HY-15310), primarily existing as a process-related impurity or potential degradation product in ivermectin-based antiparasitic formulations. epi-Ivermectin B1a can be used for the study of internal/external parasites in cattle .
Cat. No.: HY-138149
CAS No.: 106434-14-4
Synonyms: epi-Avermectin B1a
Target:
Research Areas:
2-epi-Abamectin is a degradation product of Abamectin. It is toxic to the two-spotted spider mite in a contact assay with an LC50 value of 4 ppm, which is approximately 100-fold less potent than abamectin.
Cat. No.: HY-15308R
CAS No.: 65195-55-3
Synonyms: Abamectin B1a (Standard)
Target:
Research Areas:
Avermectin B1a (Standard) is the analytical standard of Avermectin B1a. This product is intended for research and analytical applications. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
Cat. No.: HY-W783297
CAS No.: 102190-68-1
8a-OH-Avermectin B1a is a key primary monooxygenated degradate generated during the photodegradation of Avermectin B1a (HY-15308). 8a-OH-Avermectin B1a can be used for the study of antiparasitic infection .
Cat. No.: HY-137968
CAS No.: 71828-14-3
Avermectin B1a aglycon is an aglycone derivative of Avermectin B1a (HY-15308), an antiparasitic agent that paralyzes nematodes. Avermectin B1a aglycon hyperpolarizes P. crassipes muscle fibers, with a minimum effective concentration of 0.1 μM .
Cat. No.: HY-137229
CAS No.: 71831-09-9
Avermectin B1a monosaccharide is a macrolide anthelmintic that can inhibit Caenorhabditis elegans .
Cat. No.: HY-130349
CAS No.: 121124-29-6
Synonyms: L-656,748
Target:
Research Areas:
Emamectin B1a (L-656,748) is a semisynthetic derivative of avermectin B1a that binds to GABA receptors (Ki=17.6 nM in rat brain membranes) and enhances GABA responses. Emamectin B1a acitivates GABAA receptors α1β1γ2, α1β2γ2, and α1β3γ2 with IC50s of 57, 210, and 49.8 nM, respectively. Emamectin B1a also binds to glycine receptors, inhibiting glycine receptors with an IC50=218 nM in rat spinal cord. Emamectin B1a (1.067 ng/mL) caused 90% mortality of S. exigua larvae in foliar spray bioassays and topical application, making it more toxic than avermectin B1.
Target:
Research Areas:
5-O-Demethyl-28-hydroxy-Avermectin A1a is a degradation product of Avermectin B1a (HY-15308).
Cat. No.: HY-15308B
CAS No.: 110415-68-4
Target:
Research Areas:
Δ²-Avermectin B₁ₐ (Compound 3) is an antiparasitic agent targeting glutamate-gated chloride channels (GluCls) in the neuromuscular system of invertebrates. Δ²-Avermectin B₁ₐ enhances chloride ion influx, leading to hyperpolarization of the neuromuscular cell membrane, inhibition of neural signal transmission, and ultimately paralysis and death of parasites. Δ²-Avermectin B₁ₐ is promising for research of agricultural pests .
Cat. No.: HY-N8484
CAS No.: 133305-89-2
Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.
Cat. No.: HY-W1004917
CAS No.: 113665-89-7
Target:
Research Areas:
8,9-Z-Abamectin B1a is the 8,9-Z-isomer of Abamectin B1a (HY-15308). Avermectin B1a is an antiparasitic agent that paralyzes nematodes .
Cat. No.: HY-125951
CAS No.: 121424-52-0
Target:
Research Areas:
Emamectin B1b is a compound of the Avermectin family. Emamectin B1b is one component of Emamectin, accounting for approximately 90% of its content. Emamectin B1b can be used in research on inflammatory skin diseases (including neutrophilic dermatoses) .
Cat. No.: HY-126937S
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
