8,9-Z-Abamectin B1a
8,9-Z-Abamectin B1a is the 8,9-Z-isomer of Abamectin B1a (HY-15308). Avermectin B1a is an antiparasitic agent that paralyzes nematodes.
For research use only. We do not sell to patients.
- CAS No.: 113665-89-7
- Formula: C48H72O14
- Molecular Weight:873.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Parasite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
20.5 μM
Compound: AVE B1a
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Growth inhibition of mouse B16 cells by MTT method
Growth inhibition of mouse B16 cells by MTT method
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[PMID: 25611131] |
| MG-63 | IC50 |
8.6 μM
Compound: AVE B1a
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Growth inhibition of human MG63 cells by MTT method
Growth inhibition of human MG63 cells by MTT method
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[PMID: 25611131] |
| SAOS-2 | IC50 |
14.7 μM
Compound: AVE B1a
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Growth inhibition of human Saos2 cells by MTT method
Growth inhibition of human Saos2 cells by MTT method
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[PMID: 25611131] |
Chemical Information
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CAS No. 113665-89-7
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Molecular Weight 873.08
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Formula C48H72O14
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SMILES
O=C1OC(C[C@@]2(O[C@H]([C@@H](C)CC)[C@@H](C)C=C2)O3)C[C@H]3C/C=C(C)/[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)C(O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C6[C@]7(O)[C@H]1C=C(C)[C@@H](O)C7OC/6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sun Y, et al. Bioaccumulation and elimination of avermectin B1a in the earthworms (Eisenia fetida). Chemosphere. 2005 Jul;60(5):699-704. [Content Brief]
[2]. Payne GT, et al. Activation of gamma-aminobutyric acid insensitive chloride channels in mouse brain synaptic vesicles by avermectin B1a. J Biochem Toxicol. 1991 Winter;6(4):283-92. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8,9-Z-Abamectin B1a Related Classifications
HY-W1004917 Related Classifications
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