Erianin
Based on 11 publication(s) in Google Scholar
Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.
For research use only. We do not sell to patients.
- Purity: 99.62%
- CAS No.: 95041-90-0
- Formula: C18H22O5
- Molecular Weight:318.36
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Storage:
4°C, protect from light
* In solvent : -80°C, 1 year; -20°C, 6 months (protect from light)
Publications Citing Use of MedChemExpress (MCE) Erianin
More- Chem Eng J. 2024 Sep 11.
- Inflamm Res. 2026 Jan 14;75(1):19. [Abstract]
- Eur J Pharmacol. 2025 Nov 5:1006:178167. [Abstract]
- Bioorg Chem. 2024 Jun 17:150:107569. [Abstract]
- Cell Biol Int. 2021 Dec;45(12):2420-2428. [Abstract]
- Cancer Manag Res. 2025 Aug 15:17:1657-1666. [Abstract]
- Hereditas. 2024 Nov 27;161(1):48. [Abstract]
- Nutr Cancer. 2023;75(6):1473-1484. [Abstract]
- Biochem Biophys Res Commun. 2026 Mar 12:804:153353. [Abstract]
- Res Sq. 2025 Mar 03.
- Res Sq. 2024 Oct 29.
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Cell Proliferation/Viability Assay
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Cell Proliferation/Viability Assay
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WB
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 143B | IC50 |
26.8 nM
Compound: Erianin
|
Antiproliferative activity against human 143B cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human 143B cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 37804769] |
| 143B | IC50 |
41 nM
Compound: Erianin
|
Antiproliferative activity against human 143B cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human 143B cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 37804769] |
| 143B | IC50 |
58.2 nM
Compound: Erianin
|
Antiproliferative activity against human 143B cells assessed as inhibition of cell growth measured after 24 hrs by MTT assay
Antiproliferative activity against human 143B cells assessed as inhibition of cell growth measured after 24 hrs by MTT assay
|
[PMID: 37804769] |
| A-375 | IC50 |
20.6 nM
Compound: Erianin
|
Antiproliferative activity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| A549 | ED50 |
0.01 μM
Compound: 1c
|
Cytotoxic concentration required to inhibit 50% cell growth in A-549 lung carcinoma cell lines
Cytotoxic concentration required to inhibit 50% cell growth in A-549 lung carcinoma cell lines
|
[PMID: 1875350] |
| A549 | IC50 |
0.6 nM
Compound: Erianin
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37804769] |
| A549 | IC50 |
70 nM
Compound: Erianin
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| Bel-7402 | IC50 |
21.5 nM
Compound: Erianin
|
Antiproliferative activity against human Bel-7402 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human Bel-7402 cells incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| EJM | IC50 |
65 nM
Compound: Erianin
|
Antitumor activity against human EJM cells assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay
Antitumor activity against human EJM cells assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay
|
[PMID: 37804769] |
| HCC 2998 | IC50 |
70 nM
Compound: Erianin
|
Antiproliferative activity against human HCC 2998 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCC 2998 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| HCCLM3 | IC50 |
17.68 nM
Compound: Erianin
|
Antiproliferative activity against human HCCLM3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HCCLM3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 34931827] |
| HCT-116 | IC50 |
60 nM
Compound: Erianin
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| HeLa | IC50 |
0.22 μM
Compound: Erianin
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay
|
[PMID: 37804769] |
| HeLa | IC50 |
8300 nM
Compound: Erianin
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37804769] |
| HepG2 | IC50 |
119.6 nM
Compound: Erianin
|
Anticancer activity against human HepG2 cells assessed as cell growth reduction incubated for 48 hrs by MTT assay
Anticancer activity against human HepG2 cells assessed as cell growth reduction incubated for 48 hrs by MTT assay
|
[PMID: 37804769] |
| HepG2 | IC50 |
128.2 nM
Compound: Erianin
|
Anticancer activity against human HepG2 cells assessed as cell growth reduction incubated for 24 hrs by MTT assay
Anticancer activity against human HepG2 cells assessed as cell growth reduction incubated for 24 hrs by MTT assay
|
[PMID: 37804769] |
| HepG2 | IC50 |
174.8 nM
Compound: Erianin
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth
|
[PMID: 37804769] |
| HepG2 | IC50 |
43.7 nM
Compound: Erianin
|
Anticancer activity against human HepG2 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
Anticancer activity against human HepG2 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
|
[PMID: 37804769] |
| HepG2 | IC50 |
583.7 nM
Compound: Erianin
|
Antiproliferative activity against human HepG2 cells
Antiproliferative activity against human HepG2 cells
|
[PMID: 37804769] |
| HepG2 | IC50 |
72.8 nM
Compound: Erianin
|
Anticancer activity against human HepG2 cells assessed as reduction in cell viability
Anticancer activity against human HepG2 cells assessed as reduction in cell viability
|
[PMID: 37804769] |
| HepG2 | IC50 |
99.26 nM
Compound: Erianin
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 34931827] |
| HL-60 | IC50 |
0.05 μM
Compound: 24
|
Cytotoxicity of compound against HL-60 human leukemia cells
Cytotoxicity of compound against HL-60 human leukemia cells
|
[PMID: 1552500] |
| HL-60 | IC50 |
38 nM
Compound: Erianin
|
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| HL-60 | IC50 |
40 nM
Compound: Erianin
|
Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37804769] |
| HLE | IC50 |
28.6 nM
Compound: Erianin
|
Antiproliferative activity against human HLE cells
Antiproliferative activity against human HLE cells
|
[PMID: 37804769] |
| HT-29 | ED50 |
0.081 μM
Compound: 1c
|
Cytotoxic concentration required to inhibit 50% cell growth in HT-29 colon adenocarcinoma cell lines
Cytotoxic concentration required to inhibit 50% cell growth in HT-29 colon adenocarcinoma cell lines
|
[PMID: 1875350] |
| Huh-7 | IC50 |
44.3 nM
Compound: Erianin
|
Antiproliferative activity against human Huh-7 cells
Antiproliferative activity against human Huh-7 cells
|
[PMID: 37804769] |
| Ishikawa | IC50 |
40.6 nM
Compound: Erianin
|
Antiproliferative activity against human Ishikawa cells assessed as reduction in cell viability by MTS assay
Antiproliferative activity against human Ishikawa cells assessed as reduction in cell viability by MTS assay
|
[PMID: 37804769] |
| L1210 | IC50 |
0.07 μM
Compound: 24
|
Compound was tested for the inhibition of L1210 leukemia cells growth in mice
Compound was tested for the inhibition of L1210 leukemia cells growth in mice
|
[PMID: 1552500] |
| LLC-MK2 | IC50 |
2.3 nM
Compound: Erianin
|
Antiproliferative activity against Rhesus monkey LLC-MK2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against Rhesus monkey LLC-MK2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37804769] |
| LNCaP | IC50 |
26.2 nM
Compound: Erianin
|
Cytotoxicity against human LNCaP cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human LNCaP cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| LNCaP | IC50 |
26.5 nM
Compound: Erianin
|
Cytotoxicity against human LNCaP cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human LNCaP cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37804769] |
| LNCaP | IC50 |
33.8 nM
Compound: Erianin
|
Cytotoxicity against human LNCaP cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against human LNCaP cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37804769] |
| MCF7 | ED50 |
0.33 μM
Compound: 1c
|
Cytotoxic concentration required to inhibit 50% cell growth in MCF-7 breast carcinoma cell lines
Cytotoxic concentration required to inhibit 50% cell growth in MCF-7 breast carcinoma cell lines
|
[PMID: 1875350] |
| MCF7 | IC50 |
13 nM
Compound: Table 1, R4C1
|
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19135763] |
| MCF7 | IC50 |
60 nM
Compound: Erianin
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| MDA-MB-231 | IC50 |
71 nM
Compound: Erianin
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
|
[PMID: 37804769] |
| MDA-MB-468 | IC50 |
40 nM
Compound: Erianin
|
Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 37804769] |
| MHCC97 | IC50 |
386.4 nM
Compound: Erianin
|
Antiproliferative activity against human MHCC97 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human MHCC97 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 34931827] |
| MIA PaCa-2 | IC50 |
50 nM
Compound: Erianin
|
Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 37804769] |
| MLM | ED50 |
0.01 μM
Compound: 1c
|
Cytotoxic concentration required to inhibit 50% cell growth in MLM melanoma cell lines
Cytotoxic concentration required to inhibit 50% cell growth in MLM melanoma cell lines
|
[PMID: 1875350] |
| NCI-H1975 | IC50 |
0.5 nM
Compound: Erianin
|
Antiproliferative activity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37804769] |
| P388 | IC50 |
0.11 μM
Compound: 1d
|
Concentration required for 50% inhibition of P388 murine leukemia cell growth in MTT assay
Concentration required for 50% inhibition of P388 murine leukemia cell growth in MTT assay
|
[PMID: 11140732] |
| PC-3 | IC50 |
26 nM
Compound: Erianin
|
Antiproliferative activity against human PC-3 cells assessed as reduction of cell viability incubated for 24 to 72 hrs by CCK-8 assay
Antiproliferative activity against human PC-3 cells assessed as reduction of cell viability incubated for 24 to 72 hrs by CCK-8 assay
|
[PMID: 37804769] |
| PLC-PRF-5 | IC50 |
55 nM
Compound: Erianin
|
Antiproliferative activity against human PLC-PRF-5 cells
Antiproliferative activity against human PLC-PRF-5 cells
|
[PMID: 37804769] |
| SK-HEP1 | IC50 |
757.1 nM
Compound: Erianin
|
Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 34931827] |
| SK-MEL3 | IC50 |
12 nM
Compound: Erianin
|
Antiproliferative activity against human SK-MEL3 cells harboring BRAF V600E mutant assessed as reduction in cell viability by cell-titer Glo assay
Antiproliferative activity against human SK-MEL3 cells harboring BRAF V600E mutant assessed as reduction in cell viability by cell-titer Glo assay
|
[PMID: 37804769] |
| SK-MEL-5 | ED50 |
0.0021 μM
Compound: 1c
|
Cytotoxic concentration required to inhibit 50% cell growth in SKMEL-5 melanoma cell lines
Cytotoxic concentration required to inhibit 50% cell growth in SKMEL-5 melanoma cell lines
|
[PMID: 1875350] |
| SMMC-7721 | IC50 |
81 nM
Compound: Erianin
|
Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay
Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay
|
[PMID: 37804769] |
| SNU-449 | IC50 |
236.3 nM
Compound: Erianin
|
Antiproliferative activity against human SNU-449 cells
Antiproliferative activity against human SNU-449 cells
|
[PMID: 37804769] |
| T-24 | IC50 |
0.46 μM
Compound: 33
|
Anti-cancer activity against human T24 cells
Anti-cancer activity against human T24 cells
|
[PMID: 32711292] |
| T-24 | IC50 |
45.9 nM
Compound: Erianin
|
Antiproliferative activity against human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37804769] |
Erianin is often used as antipyretic and analgesic agent. Erianin belongs to bibenzyl derivatives in structure, with the activity of anti-virus, anti-bacterial, as well as anti-benign prostatic hyperplasia. Erianin has obvious damage on 2LL-IDO cells, Erianin basically has no cytotoxicity on human normal liver cell line L02, and cell viability is maintained at around 85%[1]. Erianin inhibits the growth of HeLa cells and induces apoptosis in a dose and time dependent manner, inducing cell cycle arrest at the G2/M stage. Erianin treatment also increases the expression of Bax and caspase 3, but decreases levels of Bcl 2 and phosphorylated ERK1/2[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 95041-90-0
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Appearance Solid
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Molecular Weight 318.36
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Formula C18H22O5
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Color White to off-white
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SMILES
OC1=CC(CCC2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 1 year; -20°C, 6 months (protect from light)
Publications (11)
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Journal Impact Factor
-
Most Recent
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Inflamm Res
Erianin protects chondrocytes against IL-1β-induced oxidative stress and ferroptosis by activating GPX4/STING signaling in osteoarthritis. [Abstract]2026 Jan 14;75(1):19. PMID: 41533098 -
Eur J Pharmacol
2025 Nov 5:1006:178167. PMID: 40967355 -
Bioorg Chem
The cytotoxic natural compound erianin binds to colchicine site of β-tubulin and overcomes taxane resistance. [Abstract]2024 Jun 17:150:107569. PMID: 38905886 -
Cell Biol Int
The effect and mechanism of erianin on the reversal of oxaliplatin resistance in human colon cancer cells. [Abstract]2021 Dec;45(12):2420-2428. PMID: 34351659 -
Cancer Manag Res
Erianin Suppresses Pancreatic Cancer Progression by Inducing Cell Cycle Arrest and Ferroptosis. [Abstract]2025 Aug 15:17:1657-1666. PMID: 40837329 -
Hereditas
Erianin inhibits the progression of DDP-resistant lung adenocarcinoma by regulating the Wnt/β-catenin pathway and activating the caspase-3 for apoptosis in vitro and in vivo. [Abstract]2024 Nov 27;161(1):48. PMID: 39605083 -
Nutr Cancer
Erianin Exerts Antineoplastic Effects on Esophageal Squamous Cell Carcinoma Cells by Activating the cGMP-PKG Signaling Pathway. [Abstract]2023;75(6):1473-1484. PMID: 37099024
Erianin purchased from MedChemExpress. Usage Cited in: Nutr Cancer. 2023;75(6):1473-1484. [Abstract]
Erianin (15, 30, 60, 120, 240 nM; 48 h) suppresses the viability of various ESCC cells in a dose-dependent manner, especially the TE-10 and KYSE-150 cells.(TE-1, KYSE-30, KYSE-410, KYSE-150, and TE-10 cells belong to ESCC cells)
Erianin purchased from MedChemExpress. Usage Cited in: Nutr Cancer. 2023;75(6):1473-1484. [Abstract]
Erianin (120 nM; 24 h) significantly inhibits the proliferation of TE-10 and KYSE-150 cells.
Erianin purchased from MedChemExpress. Usage Cited in: Nutr Cancer. 2023;75(6):1473-1484. [Abstract]
Erianin (120 nM; 24 h) significantly inhibits the expression of vimentin, N-cadherin and β-catenin and increases the expression of E-cadherin in TE-10 and KYSE-150 cells.
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Biochem Biophys Res Commun
Erianin induces ferroptosis in ovarian cancer cells by upregulating PDP2 and activating the JNK signaling pathway. [Abstract]2026 Mar 12:804:153353. PMID: 41619504 -
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Solvent & Solubility
DMSO : 100 mg/mL (314.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months (protect from light). When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months (protect from light). When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% Saline
Solubility: 5 mg/mL (15.71 mM); Suspended solution; Need ultrasonic
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.08 mg/mL (6.53 mM); Clear solution
This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (6.53 mM); Clear solution
This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 50% PEG300 50% Saline
Solubility: 25 mg/mL (78.53 mM); Clear solution; Need ultrasonic
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 1 year; -20°C, 6 months (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Su C, et al. Erianin inhibits indoleamine 2, 3-dioxygenase -induced tumor angiogenesis. Biomed Pharmacother. 2017 Apr;88:521-528. [Content Brief]
[2]. Li M, et al. Erianin inhibits human cervical cancer cell through regulation of tumor protein p53 via the extracellular signal-regulated kinase signaling pathway. Oncol Lett. 2018 Oct;16(4):5006-5012. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months (protect from light). When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1411 mL | 15.7055 mL | 31.4110 mL | 78.5275 mL |
| 5 mM | 0.6282 mL | 3.1411 mL | 6.2822 mL | 15.7055 mL | |
| 10 mM | 0.3141 mL | 1.5705 mL | 3.1411 mL | 7.8527 mL | |
| 15 mM | 0.2094 mL | 1.0470 mL | 2.0941 mL | 5.2352 mL | |
| 20 mM | 0.1571 mL | 0.7853 mL | 1.5705 mL | 3.9264 mL | |
| 25 mM | 0.1256 mL | 0.6282 mL | 1.2564 mL | 3.1411 mL | |
| 30 mM | 0.1047 mL | 0.5235 mL | 1.0470 mL | 2.6176 mL | |
| 40 mM | 0.0785 mL | 0.3926 mL | 0.7853 mL | 1.9632 mL | |
| 50 mM | 0.0628 mL | 0.3141 mL | 0.6282 mL | 1.5705 mL | |
| 60 mM | 0.0524 mL | 0.2618 mL | 0.5235 mL | 1.3088 mL | |
| 80 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9816 mL | |
| 100 mM | 0.0314 mL | 0.1571 mL | 0.3141 mL | 0.7853 mL |