- Natural Products
- Plants
- Orchidaceae
- Dendrobium nobile Lindl.
Dendrobium nobile Lindl.
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Dendrobium nobile Lindl. (16)
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- Formula: C18H22O5
- Molecular Weight: 318.36
Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.
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- Formula: C16H25NO2
- Molecular Weight: 263.38
Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses, with IC50s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively. Dendrobine activates the JNK/p38/Nrf2 signaling pathway. Dendrobine exhibits antiviral, antitumor, anti-inflammatory, and neuroprotective properties.
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- Formula: C16H18O4
- Molecular Weight: 274.31
Gigantol is an orally active bibenzyl compound. Gigantol targets MYC to promote its ubiquitin-proteasomal degradation and inhibit the growth of lung cancer cells. Gigantol exerts anti-lung cancer activity by inducing ferroptosis (Ferroptosis) via the SLC7A11-GPX4 axis. Gigantol restores the sensitivity of mcr-harboring multidrug-resistant bacteria to colistin. Gigantol ameliorates carbon tetrachloride-induced liver injury by inhibiting the activation of the JNK/cPLA2/12-LOX inflammatory pathway. Gigantol promotes cholesterol metabolism and progesterone biosynthesis in Leydig cells. Gigantol can be used in studies related to diseases such as lung cancer, multidrug-resistant Gram-negative bacterial infections, and acute liver injury.
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- Formula: C16H18O4
- Molecular Weight: 274.32
Gigantol isomer-1 is a bibenzyl compound derived from Dendrobium nobile. Gigantol isomer-1 shows promising therapeutic potential against cancer cells. Gigantol isomer-1 is a novel inhibitor of the Wnt/β-catenin pathway.
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- Formula: C14H14
- Molecular Weight: 182.26
Bibenzyl (s-Diphenylethane; Dibenzyl) is the parent core structure of bibenzyl-type natural products and an intermediate in organic synthesis. Hydroxyl-substituted derivatives of Bibenzyl are mainly isolated from plants such as Dendrobium (Orchidaceae) and Cannabaceae. These derivatives accumulate when plants are exposed to fungal infection and biotic stress, and exhibit antioxidant, anti-inflammatory, and anti-hepatic steatosis activities.
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- Formula: C27H44O12
- Molecular Weight: 560.63
Dendronobiloside D is a sesquiterpene glycoside that can be isolated from Dendrobium officinale. Dendronobiloside D is an immunosuppressant that promotes the differentiation of CD4+ T cells into Treg cells.
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- Formula: C32H32O8
- Molecular Weight: 544.59
Didendronbiline A is a natural phenolic compound.
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- Formula: C21H34O10
- Molecular Weight: 446.49
Dendroside G is a natural product that can be found in Dendrobium officinale.
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- Formula: C27H44O12
- Molecular Weight: 560.63
Dendronobiloside C is a natural product that can be found in dendrobium.
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- Formula: C16H25NO2
- Molecular Weight: 263.38
Dendrobine (Standard) is the analytical standard of Dendrobine. This product is intended for research and analytical applications. Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses, with IC50s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively. Dendrobine activates the JNK/p38/Nrf2 signaling pathway. Dendrobine exhibits antiviral, antitumor, anti-inflammatory, and neuroprotective properties.
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- Formula: C18H22O5
- Molecular Weight: 318.36
Erianin (Standard) is the analytical standard of Erianin. This product is intended for research and analytical applications. Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.
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- Formula: C16H16O3
- Molecular Weight: 256.30
2-Hydroxy4,7-dimethoxy-9,10-dihydrophenanthrene is a natural product, isolated from the stem of Dendrobium nobile.
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- Formula: C30H26O6
- Molecular Weight: 482.52
Phoyunnanin E, isolated from Dendrobium venustum, possesses anti-migration activity. Phoyunnanin E can be used for the research of cancer.
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- Formula: C15H16O4
- Molecular Weight: 260.29
Tristin is a PTP1B inhibitor (IC50=21.2 μM) with antioxidant and antifungal activities. Tristin inhibits lipid peroxidation and NO production in LPS-stimulated macrophages, and also exhibits activity against a variety of phytopathogenic fungi. Tristin is also able to inhibit cancer cell proliferation. Tristin can be used in the research of diseases associated with phytopathogenic fungal infection, leukemia, type 2 diabetes and inflammatory responses.
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