Dendrobium nobile Lindl.

Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.

Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses, with IC₅₀s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively. Dendrobine activates the JNK/p38/Nrf2 signaling pathway. Dendrobine exhibits antiviral, antitumor, anti-inflammatory, and neuroprotective properties.

Gigantol is an orally active bibenzyl compound. Gigantol targets MYC to promote its ubiquitin-proteasomal degradation and inhibit the growth of lung cancer cells. Gigantol exerts anti-lung cancer activity by inducing ferroptosis (Ferroptosis) via the SLC7A11-GPX4 axis. Gigantol restores the sensitivity of mcr-harboring multidrug-resistant bacteria to colistin. Gigantol ameliorates carbon tetrachloride-induced liver injury by inhibiting the activation of the JNK/cPLA2/12-LOX inflammatory pathway. Gigantol promotes cholesterol metabolism and progesterone biosynthesis in Leydig cells. Gigantol can be used in studies related to diseases such as lung cancer, multidrug-resistant Gram-negative bacterial infections, and acute liver injury.

Gigantol isomer-1 is a bibenzyl compound derived from Dendrobium nobile. Gigantol isomer-1 shows promising therapeutic potential against cancer cells. Gigantol isomer-1 is a novel inhibitor of the Wnt/β-catenin pathway.

Dendroside C is a sesquiterpene glycoside found in the stems of Dendrobium nobile.

Dendronophenol B is a (propylphenyl) bibenzyl derivative and a phenolic natural product found in Dendrobium williamsonii.

6-Hydroxy-dendroxine is a picrotoxane-type sesquiterpene alkaloid found in the stems of Dendrobium nobile Lindl.

Nobilin E is a bibenzyl derivative isolated from the stems of Dendrobium nobile. Nobilin E exerts scavenger effects through DPPH radical scavenging and ORAC peroxyl radical scavenging. Nobilin E inhibits NO production in LPS/IFN-γ-activated mouse macrophages.

Dendramine is an alkaloid found in Dendrobium nobile Lindl. It can be used in studies related to the alkaloid components of Dendrobium nobile.

Dendroside E is an emmotin-type sesquiterpene glucoside present in Dendrobium nobile and exhibits immunomodulatory-related biological activities. Dendroside E is used in research related to inflammatory and immune diseases.

Dendronobilin K is a copacamphane-type sesquiterpene that can be found in the stems of Dendrobium nobile.

Dendronbiline C is a bibenzyl derivative and picrotoxane-type non-alkaloidal sesquiterpenoid that can be found in the tubes of Dendrobium nobile.

Dendrobine-N-oxide is a dendrobine-type sesquiterpene alkaloid. It is isolated from Dendrobium nobile. Dendrobine-N-oxide inhibits neuroinflammation, reduces β-Amyloid accumulation, enhances the expression of neurotrophic factors, suppresses the hyperphosphorylation of Tau protein, and exerts anti-neuronal Apoptosis effects. Dendrobine-N-oxide shows no anticancer activity against colon cancer and pancreatic adenocarcinoma. It is used in research on neurodegenerative diseases.

Flakinin A is a sesquiterpene and anticancer agent. Flakinin A can be isolated from the whole plant of Dendrobium Snowflake 'Red Star'. Flakinin A exhibits anticancer activity against leukemia. Flakinin A can be used for research on leukemia.

Dendronobiloside E is a sesquiterpene glycoside. Dendronobiloside E can be isolated from the stems of Dendrobium nobile Lindl.

Dendronobiloliside A (Dendronobilin D-11-O-β-D-glucopyranoside) is a sesquiterpene glycoside. Dendronobiloliside A is isolated from Dendrobium nobile Lindl. Dendronobiloliside A shows no anticancer activity against liver cancer, cervical cancer, breast cancer, and non-small cell lung cancer.