Dendronobiloliside A
Dendronobiloliside A (Dendronobilin D-11-O-β-D-glucopyranoside) is a sesquiterpene glycoside. Dendronobiloliside A is isolated from Dendrobium nobile Lindl. Dendronobiloliside A shows no anticancer activity against liver cancer, cervical cancer, breast cancer, and non-small cell lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 2474950-25-7
- Formula: C21H34O10
- Molecular Weight:446.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>50 μM
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Antiproliferative activity against human HepG2 cancer cells assessed as inhibition of cell proliferation.
Antiproliferative activity against human HepG2 cancer cells assessed as inhibition of cell proliferation.
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42166685 |
| HeLa | IC50 |
>50 μM
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Antiproliferative activity against human HeLa cancer cells assessed as inhibition of cell proliferation.
Antiproliferative activity against human HeLa cancer cells assessed as inhibition of cell proliferation.
|
42166685 |
| MCF7 | IC50 |
>50 μM
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Antiproliferative activity against human MCF-7 cancer cells assessed as inhibition of cell proliferation.
Antiproliferative activity against human MCF-7 cancer cells assessed as inhibition of cell proliferation.
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42166685 |
| A549 | IC50 |
>50 μM
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Antiproliferative activity against human A549 cancer cells assessed as inhibition of cell proliferation.
Antiproliferative activity against human A549 cancer cells assessed as inhibition of cell proliferation.
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42166685 |
In Vitro
Chemical Information
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CAS No. 2474950-25-7
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Molecular Weight 446.49
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Formula C21H34O10
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SMILES
C[C@]12[C@](CC[C@H]2CO[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)([H])[C@]4([H])C([C@](OC4=O)([H])[C@H]1O)C(C)CO
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Synonyms
Dendronobilin D-11-O-β-D-glucopyranoside
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dendronobiloliside A Related Classifications
HY-N19540 Related Classifications
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