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Cat. No.: HY-N21755

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Nobilin E

Nobilin E is a bibenzyl derivative isolated from the stems of Dendrobium nobile. Nobilin E exerts scavenger effects through DPPH radical scavenging and ORAC peroxyl radical scavenging. Nobilin E inhibits NO production in LPS/IFN-γ-activated mouse macrophages.

For research use only. We do not sell to patients.

CAS No.: 924895-49-8
Formula: C₃₂H₃₂O₈
Molecular Weight:544.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Nobilin E Chemical Structure

CAS No.: 924895-49-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC50	19.2 μM	Inhibition of NO production in LPS and IFN-γ-activated murine RAW 264.7 macrophages incubated for approximately 16 hrs and measured by Griess reagent colorimetric quantitation at 570 nm. Inhibition of NO production in LPS and IFN-γ-activated murine RAW 264.7 macrophages incubated for approximately 16 hrs and measured by Griess reagent colorimetric quantitation at 570 nm.	17253844

In Vitro

Nobilin E (compound 2) (30 min) shows potent antioxidant activity in the DPPH free radical scavenging assay with an IC₅₀ of 21.0 μM^[1].
Nobilin E inhibits NO production in LPS and IFN-γ-activated RAW 264.7 murine macrophages with an IC₅₀ of 19.2 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 924895-49-8
Molecular Weight 544.60
Formula C₃₂H₃₂O₈
SMILES

C(C1C=2C(OC=3C1=CC(O)=C(O)C3OC)=C(O)C(OC)=CC2CCC4=CC(OC)=CC=C4)C5=CC=C(OC)C=C5
Structure Classification
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang X, et al. Bioactive bibenzyl derivatives and fluorenones from Dendrobium nobile. Journal of natural products. 2007 Jan;70(1):24-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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