1. Peptides

PACAP-Related Peptide (PRP), human 

Cat. No.: HY-P1511
Handling Instructions

PACAP-Related Peptide (PRP), human is a 29 amino-acid region of the PACAP precursor protein. Sequence: Asp-Val-Ala-His-Gly-Ile-Leu-Asn-Glu-Ala-Tyr-Arg-Lys-Val-Leu-Asp-Gln-Leu-Ser-Ala-Gly-Lys-His-Leu-Gln-Ser-Leu-Val-Ala;DVAHGILNEAYRKVLDQLSAGKHLQSLVA.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

PACAP-Related Peptide (PRP), human Chemical Structure

PACAP-Related Peptide (PRP), human Chemical Structure

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500 μg USD 120 Get quote
1 mg USD 160 Get quote
5 mg USD 480 Get quote

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PACAP-Related Peptide (PRP), human is a 29 amino-acid region of the PACAP precursor protein. Sequence: Asp-Val-Ala-His-Gly-Ile-Leu-Asn-Glu-Ala-Tyr-Arg-Lys-Val-Leu-Asp-Gln-Leu-Ser-Ala-Gly-Lys-His-Leu-Gln-Ser-Leu-Val-Ala;DVAHGILNEAYRKVLDQLSAGKHLQSLVA.

In Vitro

PACAP-Related Peptide (PRP) has a distinct biological activity on the gallbladder that is similar to pituitary adenylate cyclase activating polypeptide (PACAP) but opposite to that of vasoactive intestinal polyprptide (VIP); and its related peptide, peptide histidine methlonmc (PHM)[1].

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
References
Molecular Weight

3146.57

Formula

C₁₃₉H₂₂₉N₄₁O₄₂

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
PACAP-Related Peptide (PRP), human
Cat. No.:
HY-P1511
Quantity:

PACAP-Related Peptide (PRP), human

Cat. No.: HY-P1511