1. Membrane Transporter/Ion Channel
  2. Proton Pump
  3. Vonoprazan

Vonoprazan (Synonyms: TAK-438 (free base))

Cat. No.: HY-100007 Purity: 99.33%
Handling Instructions

Vonoprazan (TAK-438 free base) is an orally active potassium-competitive acid blocker which inhibits H+, K+-ATPase activity with an IC50 of 19 nM.

For research use only. We do not sell to patients.

Vonoprazan Chemical Structure

Vonoprazan Chemical Structure

CAS No. : 881681-00-1

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
50 mg USD 60 In-stock
Estimated Time of Arrival: December 31
100 mg USD 84 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Vonoprazan (TAK-438 free base) is an orally active potassium-competitive acid blocker which inhibits H+, K+-ATPase activity with an IC50 of 19 nM.

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 33 mg/mL (95.54 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8953 mL 14.4764 mL 28.9528 mL
5 mM 0.5791 mL 2.8953 mL 5.7906 mL
10 mM 0.2895 mL 1.4476 mL 2.8953 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

345.39

Formula

C₁₇H₁₆FN₃O₂S

CAS No.

881681-00-1

SMILES

O=S(N1C=C(CNC)C=C1C2=CC=CC=C2F)(C3=CC=CN=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Vonoprazan
Cat. No.:
HY-100007
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Vonoprazan

Cat. No.: HY-100007