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  4. Drug Intermediate

Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (4376):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-174476
    HSP90i
    HSP90i is a HSP90 inhibitor. HSP90i can be used as a drug intermediate to synthesize LYTACs, such as dPDL1-4 (HY-174468).
    HSP90i
  • HY-W784623
    Boc-PNA-A(Z)-OH
    Boc-PNA-A(Z)-OH is a Boc-protected peptide nucleic acid monomer with a benzyloxycarbonyl protecting group on the adenine base.
    Boc-PNA-A(Z)-OH
  • HY-159623
    Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl
    Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl is a synthetic intermediate for molecular glues. Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl can be used to synthesize GSPT1 degrader-9 (HY-159610).
    Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl
  • HY-B1419R
    Salicyl alcohol (Standard)
    Soyasaponin Aa (Standard) is the analytical standard of Soyasaponin Aa. This product is intended for research and analytical applications. Soyasaponin Aa is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ).
    Salicyl alcohol (Standard)
  • HY-W008097R
    3,3-Dimethylglutaric acid (Standard)
    3,3-Dimethylglutaric acid (Standard) is the analytical standard of 3,3-Dimethylglutaric acid (HY-W008097). This product is intended for research and analytical applications. 3,3-Dimethylglutaric acid is a type of methyl-branching fatty acid and is an occasional endogenous metabolite found in human urine. 3,3-Dimethylglutaric acid can be used as a ligand to synthesize metal complexes.
    3,3-Dimethylglutaric acid (Standard)
  • HY-P4559
    H-Pro-Met-OH
    H-Pro-Met-OH is a dipeptide containing proline and methionine. H-Pro-Met-OH also serves as a substrate for prolinase and prolyl dipeptidase.
    H-Pro-Met-OH
  • HY-N3007R
    Naringenin chalcone (Standard)
    Naringenin chalcone (Standard) is an analytical standard of Naringenin chalcone. This product is intended for research and analytical applications. Naringenin chalcone is an orally active intermediate in the biosynthesis of flavonols. Naringenin chalcone induces apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties.
    Naringenin chalcone (Standard)
  • HY-W750064
    Acetophenone-13C8
    Acetophenone-13C8 (1-Phenylethan-1-One-13C8) is the 13C-labeled Acetophenone (HY-Y0989). Acetophenone (1-Phenylethan-1-One) is an organic compound with simple structure. Acetophenone can be bioreduced to phenylethanol (PEA).
    Acetophenone-<sup>13</sup>C<sub>8</sub>
  • HY-138302
    PF-06862309
    PF-06862309 is a PF-06843195 (HY-131972) phosphate ester prodrug. PF-06862309 can be hydrolyzed to PF-06843195 in the presence of alkaline phosphatase. PF-06843195 is a highly selective PI3Kα inhibitor. PF-06862309 can be used for the study of breast cancer with ER+, HER2-, and PIK3CA mutations.
    PF-06862309
  • HY-186211
    cis,cis,trans-Diamminedichlorodisuccinatoplatinum(IV)
    cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) is a photocatalytic prodrug of Cisplatin (HY-17394), which can be activated into the active Pt (II) form. In the presence of an electron donor, cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) undergoes a photocatalytic reduction reaction catalyzed by flavoproteins to produce Cisplatin. cis,cis,trans-Diamminedichlorodisuccinatoplatinum (IV) can be used in cancer research.
    cis,cis,trans-Diamminedichlorodisuccinatoplatinum(IV)
  • HY-139563
    Lenalidomide-C10-OH
    Lenalidomide-C10-OH (6a) is an intermediate in the synthesis of INY-03-041.
    Lenalidomide-C10-OH
  • HY-P3519
    ACV Tripeptide
    		98.74%
    ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics.
    ACV Tripeptide
  • HY-186158
    HOOC-OXA-COOH
    HOOC-OXA-COOH is an anionic prodrug of Oxaliplatin (HY-17371). HOOC-OXA-COOH can be loaded onto nanomotors via electrostatic interaction, and undergoes cascade activation by H2S and endogenous glutathione in the tumor microenvironment to release cytotoxic Pt2+. HOOC-OXA-COOH can be used in the research of colon cancer.
    HOOC-OXA-COOH
  • HY-W722128
    Olivetolic acid-d9
    Olivetolic acid-d9 is the deuterium labeled Olivetolic acid (HY-W090292). Olivetolic acid is a biosynthetic precursor of cannabinol acid (CBGA). Olivetolic acid has anticonvulsant activity.
    Olivetolic acid-d<sub>9</sub>
  • HY-W007328S
    5-Methoxyindole-d3
    5-Methoxyindole-d3 is the deuterium labeled 5-Methoxyindole (HY-W007328). 5-Methoxyindole is an endogenous compound with significant biological activity, which is produced by the metabolism of L-tryptophan. 5-Methoxyindole can be used as a drug intermediate to synthesize 5-methoxytryptophan and N-acetyl 5-methoxytryptamine, and it exhibits anti-cancer and anti-inflammatory activities.
    5-Methoxyindole-d<sub>3</sub>
  • HY-123193
    Avizafone
    Avizafone (Pro-diazepam), a pro-drug of Diazepam, is an anticonvulsant agent. Avizafone can be used as an antidote of nerve agent poisoning. In vivo, Avizafone is rapidly hydrolyzed by aminopeptidase to produce lysine and diazepam. Avizafone has research areas including neurological disease, such as epilepsy.
    Avizafone
  • HY-W710036
    Erythromycin A 9-oxime-d3
    Erythromycin A 9-oxime-d3 is the deuterium labeled Erythromycin oxime (HY-134518). Erythromycin oxime is an intermediate of Azithromycin (HY-17506). Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
    Erythromycin A 9-oxime-d<sub>3</sub>
  • HY-W291369
    Crotonamide
    Crotonamide is a drug intermediate that can be used for the synthesis of EGFR inhibitors.
    Crotonamide
  • HY-W750144
    Phenylglyoxylic acid-13C8
    Phenylglyoxylic acid-13C8 (Benzoylformic acid-13C8) is the 13C-labeled Phenylglyoxylic acid (HY-W010255). Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds.
    Phenylglyoxylic acid-<sup>13</sup>C<sub>8</sub>
  • HY-N6888R
    Rebaudioside E (Standard)
    Rebaudioside E (Standard) is the analytical standard of Rebaudioside E. This product is intended for research and analytical applications. Rebaudioside E is a steviol glycoside and also a high-intensity sweetener. The sweetness of Rebaudioside E is 150-300 times that of sucrose. Rebaudioside E serves as a precursor for the biosynthesis of Rebaudioside D (HY-N0468) and Rebaudioside M (HY-N6833).
    Rebaudioside E (Standard)