Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4630)
Related Products (4630)
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Euchrenone B1
0 ImagesCat. No.: HY-N20709CAS No.: 119061-09-5Euchrenone B1 is a flavonoid. Euchrenone B1 can be isolated from the stem bark of Maackia amurensis and the roots of Euchresta formosana. Euchrenone B1 exhibits anticancer activity against cervical cancer, melanoma, breast cancer, and liver cancer.
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Elsulfavirine sodium
0 ImagesCat. No.: HY-109056ACAS No.: 867365-40-0Synonyms: R-1206 sodiumElsulfavirine sodium (R-1206) is an orally active human carbonic anhydrase (carbonic anhydrase, CA) inhibitor and an allosteric inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRT). Elsulfavirine sodium also targets and blocks the interaction between adenylosuccinate lyase (ADSL) and insulin-induced gene proteins INSIG1/2, blocks SREBP-1-mediated de novo lipid synthesis, and inhibits the proliferation of liver cancer cells. The combination of Elsulfavirine sodium and Lenvatinib (HY-10981) produces a synergistic anti-tumor effect. Elsulfavirine sodium is converted into the active metabolite VM1500A in vivo, blocks the DNA polymerase activity of reverse transcriptase, and inhibits HIV-1 replication. Elsulfavirine sodium exhibits a Ki of 1960 nM-52400 nM against human carbonic anhydrase isoforms including I, VII, VI, VA, VB, IX, XIII, XIV. Elsulfavirine sodium is used in studies related to HIV-1 infection and liver cancer.
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N-Ethylnicotinamide
0 ImagesN-Ethylnicotinamide is a compound with weak vasodilatory activity. N-Ethylnicotinamide also serves as the core scaffold of the antianginal agent Nicorandil (HY-B0341) and its derivatives.
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H-Tyr-Gly-OH
0 ImagesCat. No.: HY-W343771CAS No.: 673-08-5H-Tyr-Gly-OH is an amino acid building block commonly used in biochemical and peptide synthesis.
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Atorvastatin acetonide tert-butyl ester (Standard)
0 ImagesAtorvastatin acetonide tert-butyl ester (Standard) is the analytical standard of Atorvastatin acetonide tert-butyl ester. This product is intended for research and analytical applications. Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
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Bibenzyl
0 ImagesBibenzyl (s-Diphenylethane; Dibenzyl) is the parent core structure of bibenzyl-type natural products and an intermediate in organic synthesis. Hydroxyl-substituted derivatives of Bibenzyl are mainly isolated from plants such as Dendrobium (Orchidaceae) and Cannabaceae. These derivatives accumulate when plants are exposed to fungal infection and biotic stress, and exhibit antioxidant, anti-inflammatory, and anti-hepatic steatosis activities.
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Fingolimod impurity 3
0 ImagesCat. No.: HY-108399CAS No.: 162358-08-9
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Ac4GlcNAcF3
0 ImagesCat. No.: HY-W699962CAS No.: 137766-83-7Ac4GlcNAcF3 is a cell-permeable glycomimetic that can be recognized and utilized by OGT and is resistant to hydrolysis by OGA. GlcNAcF3, the active metabolite of Ac4GlcNAcF3, can be recognized by OGT as a substrate for peptide modification. Ac4GlcNAcF3 upregulates the level of cellular O-GlcNAc modification. Ac4GlcNAcF3 can be used in studies related to glycosylation regulation.
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Fmoc-DON-Boc
0 ImagesCat. No.: HY-153151CAS No.: 1998724-98-3Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist.
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(Z)-2-Pyridinecarboxamidoxime
0 ImagesCat. No.: HY-W1057948CAS No.: 849833-60-9(Z)-2-Pyridinecarboxamidoxime is an isomer of 2-Pyridinecarboxamidoxime and also a type of pharmaceutical intermediate. (Z)-2-Pyridinecarboxamidoxime can be used in studies related to organic synthesis.
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(R)-(-)-2-Butanol (Standard)
0 ImagesGinsenoside Rg1 (Standard) is the analytical standard of Ginsenoside Rg1. This product is intended for research and analytical applications. Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.
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Pirisudanol
0 ImagesCat. No.: HY-165323CAS No.: 33605-94-6Synonyms: PyrisuccideanolPirisudanol (pyrisuccideanol) is a psychostimulant. Pirisudanol can be used for the research of neurological disease, such as depression.
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BTN3A1 ligand-1
0 ImagesCat. No.: HY-170956BTN3A1 ligand-1 (Compound 26b) is a triazole-containing aryl/acyloxyalkyl phosphonate prodrug. BTN3A1 ligand-1 can stimulate T cell proliferation (EC50 : 0.49 nM) and interferon γ secretion. BTN3A1 ligand-1 has certain plasma stability and can be used in related immunotherapy research.
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3-Phenanthrylamine
0 ImagesCat. No.: HY-W353231CAS No.: 1892-54-23-Phenanthrylamine is an intermediate. 3-Phenanthrylamine has potential breast carcinogenic activity.
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3-Methylcatechol (Standard)
0 Images3-Methylcatechol (Standard) is the analytical standard of 3-Methylcatechol (HY-W012815). This product is intended for research and analytical applications. 3-Methylcatechol is a phenolic derivative that can be produced by Pseudomonas putida MC2. 3-Methylcatechol can serve as a molecular building block in chemical synthesis to produce other active compounds.
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AldoView precursor-1
0 ImagesCat. No.: HY-180534CAS No.: 2786716-47-8AldoView precursor-1 (Compound 7) is the key labeling precursor for the synthetic radioactive PET tracer [18F] AldoView. [18F] AldoView is a selective aldosterone synthase PET tracer used for imaging in primary hyperaldosteronism.
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Citreomontanin
0 ImagesCat. No.: HY-N16412CAS No.: 74474-66-1Synonyms: CitreomontanineCitreomontanin (Citreomontanine) (Compound 3), an α‑Pyrone polyketide, is an intermediate of Citreoviripyrone A. Citreomontanin can be isolated from the mycelium of endophytic Penicillium sp. in Catharanthus roseus. Citreoviripyrone A has a moderate inhibitory activity on HCT116 cells growth.
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AF299
0 ImagesCat. No.: HY-162375CAS No.: 832685-79-7AF299 can reduce collagen-related peptide-induced platelet Ca2+ rises and collagen-induced platelet aggregation. AF299 can be used for research of antiplatelet research.
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5α-Cholestane-d2
0 ImagesCat. No.: HY-133970S1CAS No.: 122241-86-55α-Cholestane-d2 is the deuterium labeled 5α-Cholestane (HY-133970). 5α-Cholestane is a skeleton. 5α-Cholestane can be used in the synthesis of Brassinosteroids. 5α-Cholestane can be used in skeletal muscle research.
