Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4714)
Related Products (4714)
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Justalakonin
0 ImagesCat. No.: HY-N21658CAS No.: 602331-39-5Justalakonin is an arylnaphthalene glycoside that is found in Justicia purpurea. Justalakonin exhibits no significant inhibitory effects on lipid peroxidation, COX‑1, or the proliferation of various tumor cells, but possesses COX-2 inhibitory activity.
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H-Val-Val-OH-13C10,15N2 TFA
0 ImagesCat. No.: HY-126584SSynonyms: Val-val-13C10,15N2H-Val-Val-OH-13C10,15N2 TFA (Val-val-13C10,15N2) is the 13C- and 15N-labeled H-Val-Val-OH (HY-126584). H-VAL-VAL-OH (Val-val) is a dipeptide in which two valine (Val) residues are linked by an amide bond. H-VAL-VAL-OH can be used for the synthesis of some important compounds such as Poststatin (HY-125432).
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DMBA-SIL-PNP
0 ImagesCat. No.: HY-160703CAS No.: 2923885-47-4DMBA-SIL-PNP (Compound 5) is an intermediate used for preparing Drug-Linker Conjugates, which can be applied in cancer research.
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3-Methyl-2(5H)-furanone
0 ImagesCat. No.: HY-W142497CAS No.: 22122-36-73-Methyl-2(5H)-furanone is the common structural unit in natural and several synthetic strigolactones, which are germination stimulants for seeds of the parasitic weeds Striga and Orobanche spp..
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Ranolazine impurity 10
0 ImagesCat. No.: HY-W016487CAS No.: 2210-74-4Ranolazine impurity 10 is an impurity of Ranolazine.
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Capecitabine 2',3'-diacetate-d11
0 ImagesCat. No.: HY-W765881Capecitabine 2',3'-diacetate-d11 is the deuterium labeled Capecitabine 2',3'-diacetate (HY-W099488). Capecitabine 2',3'-diacetate (Compound 10b) is the prodrug for the antitumor agent Capecitabine (HY-B0016).
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LBA-NHS
0 ImagesCat. No.: HY-171713CAS No.: 96607-63-5
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5-endo-Hydroxyborneol
0 ImagesCat. No.: HY-N16572CAS No.: 68738-10-35-endo-Hydroxyborneol is a hydroxylation metabolite of a monoterpene compound. 5-endo-Hydroxyborneol can be used as a drug intermediate to synthesize optically pure compounds.
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Fmoc-PNA-U-OH
0 ImagesCat. No.: HY-W665456CAS No.: 959151-70-3Fmoc‑PNA‑U‑OH is a peptide nucleic acid monomer that can be used for the synthesis of peptide nucleic acids (PNAs). Fmoc‑PNA‑U‑OH exhibits specific binding to adenine, resistance to enzymatic degradation, and strong hybridization properties. Fmoc‑PNA‑U‑OH can be applied in research fields such as gene diagnosis, molecular biology, and antisense therapy.
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Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP
0 ImagesCat. No.: HY-164340CAS No.: 2874333-81-8Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP (Compound 16) is a β-glucuronide-type linker precursor that couples with NeoDegrader P1 to synthesize the NeoDegrader P1-β-Glucuronide Linker Complex. Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP and its derived linker-payload complexes can be used for the research of acute myeloid leukemia.
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pCR8
0 ImagesCat. No.: HY-174460pCR8 is a CR8 prodrug and anticancer agent responsive to H2O2. pCR8 achieves selective release of CR8 via boronate ester oxidation mediated by elevated hydrogen peroxide levels at tumor sites, self-assembles into nanoparticles, and degrades cell cycle-related proteins. A synergistic effect is produced when pCR8 is used in combination with immune checkpoint inhibitors. pCR8 can be used for the research of triple-negative breast cancer.
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5-Hydroxyisatin
0 ImagesCat. No.: HY-W092549CAS No.: 116569-09-65-Hydroxyisatin can be used to synthesize anti-cancer agents.
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1-Amino-3-(phosphonooxy)-2-propanone
0 ImagesCat. No.: HY-176959CAS No.: 205189-34-01-Amino-3-(phosphonooxy)-2-propanone is a drug intermediate that can be used for the synthesis of vitamin B6.
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L-Cystine N-carboxyanhydride
0 ImagesCat. No.: HY-44680CAS No.: 51507-96-1L-Cystine N-carboxyanhydride can be used for synthesis of polyamino acid carrier for anti-tumor agent delivery.
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Cys-CPP44
0 ImagesCat. No.: HY-P11926Cys-CPP44 is a cell-penetrating peptide with a Cys introduced at the N-terminus, which can specifically penetrate hepatocellular carcinoma cells. Modification with Cys-CPP44 promotes the specific penetration of arsenic trioxide-loaded liposomes into hepatocellular carcinoma cells and enhances the cellular uptake of liposomes by these cells. Cys-CPP44 can be used for the research of hepatocellular carcinoma.
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Antiproliferative agent-3
0 ImagesCat. No.: HY-145866Antiproliferative agent-3 is an antiproliferative agent. Antiproliferative agent-3 exhibits anticancer activity against a variety of cancers, including estrogen receptor-positive breast cancer. Antiproliferative agent-3 shows no toxicity to wild-type zebrafish embryos. Antiproliferative agent-3 can be used in the research of chronic myeloid leukemia, promyelocytic leukemia, Burkitt's lymphoma, estrogen receptor-positive mammary adenocarcinoma, cervical cancer, and lung cancer.
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FI-3
0 ImagesCat. No.: HY-N16458CAS No.: 1316171-50-2FI-3 is a polycyclic tetramate macrolactam biosynthetic intermediate found in Streptomyces sp. SPB78. FI-3 is promising for research of antibiotics.
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4,7-Dichloroquinoline-15N
0 ImagesCat. No.: HY-59243SCAS No.: 366495-92-34,7-Dichloroquinoline-15N is the 15N labeled 4,7-Dichloroquinoline (HY-59243). 4,7-Dichloroquinoline is a dichloro-substituted quinoline that can be used for the synthesis of other active compounds.
