Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP
Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP (Compound 16) is a β-glucuronide-type linker precursor that couples with NeoDegrader P1 to synthesize the NeoDegrader P1-β-Glucuronide Linker Complex. Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP and its derived linker-payload complexes can be used for the research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 2874333-81-8
- Formula: C35H41N3O18
- Molecular Weight:791.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Boc-NH-PAB (triacetyl-β-D-glucopyranuronate)-PNP is a linker-payload intermediate used for subsequent conjugation with antibodies to construct intact DACs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2874333-81-8
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Molecular Weight 791.71
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Formula C35H41N3O18
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SMILES
CC(O[C@H]([C@H]([C@@H]([C@H](O1)C(OC)=O)OC(C)=O)OC(C)=O)[C@@H]1OC2=C(C=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)C(NCCNC(OC(C)(C)C)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP Related Classifications
HY-164340 Related Classifications
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