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Cat. No.: HY-N20709

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Euchrenone B1

Euchrenone B1 is a flavonoid. Euchrenone B1 can be isolated from the stem bark of Maackia amurensis and the roots of Euchresta formosana. Euchrenone B1 exhibits anticancer activity against cervical cancer, melanoma, breast cancer, and liver cancer.

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CAS No.: 119061-09-5
Formule: C₃₀H₃₄O₅
Masse moléculaire:474.60

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Euchrenone B1 Chemical Structure

CAS No.: 119061-09-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

In Vitro

Anti-cancer

Euchrenone B1 (48 h) potently inhibits the growth of HeLa, A375S2, MCF-7, and HepG2 human cancer cell lines in vitro, with the highest potency against HeLa cells (IC₅₀ = 4.5 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

A375S2, HeLa, MCF-7, HepG2
Concentration:

Various concentrations
Incubation Time:

48 h
Result:

Exhibited dose-dependent cytotoxicity against all four tested human cancer cell lines, with IC₅₀ values of 14.8 μM for A375S2, 4.5 μM for HeLa, 13.1 μM for MCF-7, and 32.9 μM for HepG2.
Showed the most potent cytotoxicity against the HeLa cell line among all tested compounds.

Related Protocols :

Chemical Information

CAS No. 119061-09-5
Masse moléculaire 474.60
Formule C₃₀H₃₄O₅
SMILES

O=C1C(=COC2=C1C(O)=C(C(O)=C2CC=C(C)C)CC=C(C)C)C=3C=CC(O)=C(C3)CC=C(C)C
Structure Classification
- Flavonoids
- Isoflavones
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Li X, et al. Cytotoxic prenylated flavonoids from the stem bark of Maackia amurensis. Chemical & pharmaceutical bulletin. 2009 Mar;57(3):302-6. [Content Brief]

[2]. Lo W L, et al. The constituents of Euchresta formosana[J]. Journal of the Chinese Chemical Society, 2002, 49(3): 421-426.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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