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  4. Drug Intermediate

Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (4377):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-47513
    (2R,7aS)-Isopropyl 2-fluorohexahydro-1H-pyrrolizine-7a-carboxylate
    		99.8%
    (2R,7aS)-Isopropyl 2-fluorohexahydro-1H-pyrrolizine-7a-carboxylate is a drug intermediate for synthesis of various active compounds.
    (2R,7aS)-Isopropyl 2-fluorohexahydro-1H-pyrrolizine-7a-carboxylate
  • HY-23703A
    5-(Piperazin-1-yl)isoquinoline hydrochloride
    		99.60%
    5-(Piperazin-1-yl)isoquinoline hydrochloride is a drug intermediate for synthesis of various active compounds.
    5-(Piperazin-1-yl)isoquinoline hydrochloride
  • HY-118292
    Hydroquinone diacetate
    		98.30%
    Hydroquinone diacetate (1,4-Diacetoxybenzene) is a diester product and also a commonly used synthetic intermediate for agrochemicals and fine chemicals. Hydroquinone diacetate can be produced via the acetylation of hydroquinone (HY-B0951) with acetic anhydride.
    Hydroquinone diacetate
  • HY-I0459
    Apixaban impurity 41
    		99.88%
    Apixaban impurity 41 is an impurity of Apixaban (HY-50667).
    Apixaban impurity 41
  • HY-W101682
    (S)-Pregabalin methyl ester hydrochloride
    (S)-Pregabalin methyl ester hydrochloride is a methyl ester form of Pregabalin.
    (S)-Pregabalin methyl ester hydrochloride
  • HY-W105506
    Dimethylpropiothetin hydrochloride
    		99.93%
    Dimethylpropiothetin hydrochloride is a dimethylsulfide precursor. Dimethylpropiothetin hydrochloride can be isolated from the marine coccolithophore Hymenomonas carterae. Dimethylpropiothetin hydrochloride participates in the maintenance of cellular osmotic pressure.
    Dimethylpropiothetin hydrochloride
  • HY-60218
    1-Boc-3-(hydroxymethyl)pyrrolidine
    1-Boc-3-(hydroxymethyl)pyrrolidine is an intermediate. 1-Boc-3-(hydroxymethyl)pyrrolidine can be used to synthesize a FGFR1/2/3/4 inhibitor (Compound 2). 1-Boc-3-(hydroxymethyl)pyrrolidine can be used in cancer research.
    1-Boc-3-(hydroxymethyl)pyrrolidine
  • HY-W022880
    4-Bromo-6-fluoro-1H-indazole
    		98.44%
    4-Bromo-6-fluoro-1H-indazole is a drug synthesis intermediate that can be used to synthesize an inhibitor of hematopoietic progenitor kinase 1 (hpk1).
    4-Bromo-6-fluoro-1H-indazole
  • HY-Y1778
    N-(Diphenylmethylene)glycine tert-butyl ester
    		99.90%
    N-(Diphenylmethylene)glycine tert-butyl ester is a protected glycine derivative. N-(Diphenylmethylene)glycine tert-butyl ester undergoes enantioselective alkylation to produce α-alkyl-α-amino acid derivatives.
    N-(Diphenylmethylene)glycine tert-butyl ester
  • HY-W090292
    Olivetolic acid
    		99.90%
    Olivetolic acid is a biosynthetic precursor of cannabinol acid (CBGA). Olivetolic acid exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome. Olivetolic acid can be used for the study of convulsion.
    Olivetolic acid
  • HY-41984
    Diacetone-D-glucose
    		98.70%
    Diacetone-D-glucose (D-Glucose diacetonide) is a sugar-derived secondary alcohol that serves as an important pharmaceutical intermediate for the synthesis of other active compounds.
    Diacetone-D-glucose
  • HY-177106
    ADT-1004
    		98.16%
    ADT-1004 is an orally active prodrug of ADT-007 (HY-157887). ADT-007 is a reversible, highly potent and selective pan-RAS inhibitor that binds to the nucleotide-free conformation of RAS proteins and blocks their GTP activation, thereby inhibiting the downstream MAPK and AKT signaling pathways. ADT-1004 can be used for the research of pancreatic ductal adenocarcinoma.
    ADT-1004
  • HY-W005118
    2-Amino-4-fluoropyridine
    		99.97%
    2-Amino-4-fluoropyridine (4-Fluoropyridin-2-amine) is a drug intermediate that can be used for the synthesis reversible-covalent FGFR4 inhibitors.
    2-Amino-4-fluoropyridine
  • HY-P11498
    Cyclomarin monomer-2
    Cyclomarin monomer-2 (Compound 10), a cyclomarin monomer, is a pre-dimerization precursor that can form Homo-BacPROTACs targeting the degradation of ClpC1. Cyclomarin monomer-2 binds to the Mtb ClpC1 protein with a KD of 4.0 nM. The MIC of Cyclomarin monomer-2 against the Mtb H37Rv standard strain is 3.1 μM. Cyclomarin monomer-2 can be used as a key intermediate in the development of Homo-BacPROTACs.
    Cyclomarin monomer-2
  • HY-N7700C
    L-Guluronic acid sodium salt
    		99.95%
    L-Guluronic acid sodium salt is an uronic acid that can produce D-glucosaccharic acid on oxidation.
    L-Guluronic acid sodium salt
  • HY-W008097
    3,3-Dimethylglutaric acid
    		98.92%
    3,3-Dimethylglutaric acid, a member of methyl-branched fatty acids, is a endogenous metabolite occasionally found in human urine. 3,3-Dimethylglutaric acid can be used as a ligand to synthesize metal complexes.
    3,3-Dimethylglutaric acid
  • HY-W023023
    3-Carboxy-6-hydroxycoumarin
    		99.95%
    3-Carboxy-6-hydroxycoumarin is an intermediate in organic syntheses.
    3-Carboxy-6-hydroxycoumarin
  • HY-30014
    4-Bromo-7-azaindole
    		99.96%
    4-Bromo-7-azaindole is a brominated derivative of 7-azaindole. 4-Bromo-7-azaindole serves as a substrate for palladium-catalyzed C-N and C-O cross-coupling reactions, reacting with amides, amines, amino acid esters and phenols.
    4-Bromo-7-azaindole
  • HY-W004360
    BIBR 1087 SE
    BIBR 1087 SE is an intermediate metabolite of dabigatran etexilate.
    BIBR 1087 SE
  • HY-W001242
    1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester
    		≥98.0%
    1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester is a pharmaceutical intermediate used in the synthesis of naphthyl FXIa/PKa inhibitors.
    1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester