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  3. 4-Fluoro-5-hydroxy-2-methylindole

4-Fluoro-5-hydroxy-2-methylindole is a drug intermediate for synthesis of various active compounds.

For research use only. We do not sell to patients.

4-Fluoro-5-hydroxy-2-methylindole

4-Fluoro-5-hydroxy-2-methylindole Chemical Structure

CAS No. : 288385-88-6

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Description

4-Fluoro-5-hydroxy-2-methylindole is a drug intermediate for synthesis of various active compounds.

Molecular Weight

165.17

Formula

C9H8FNO

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=C(F)C2=C(NC(C)=C2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (605.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0544 mL 30.2718 mL 60.5437 mL
5 mM 1.2109 mL 6.0544 mL 12.1087 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.88%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.0544 mL 30.2718 mL 60.5437 mL 151.3592 mL
5 mM 1.2109 mL 6.0544 mL 12.1087 mL 30.2718 mL
10 mM 0.6054 mL 3.0272 mL 6.0544 mL 15.1359 mL
15 mM 0.4036 mL 2.0181 mL 4.0362 mL 10.0906 mL
20 mM 0.3027 mL 1.5136 mL 3.0272 mL 7.5680 mL
25 mM 0.2422 mL 1.2109 mL 2.4217 mL 6.0544 mL
30 mM 0.2018 mL 1.0091 mL 2.0181 mL 5.0453 mL
40 mM 0.1514 mL 0.7568 mL 1.5136 mL 3.7840 mL
50 mM 0.1211 mL 0.6054 mL 1.2109 mL 3.0272 mL
60 mM 0.1009 mL 0.5045 mL 1.0091 mL 2.5227 mL
80 mM 0.0757 mL 0.3784 mL 0.7568 mL 1.8920 mL
100 mM 0.0605 mL 0.3027 mL 0.6054 mL 1.5136 mL
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4-Fluoro-5-hydroxy-2-methylindole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
4-Fluoro-5-hydroxy-2-methylindole
Cat. No.:
HY-65268
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