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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
Valproic acid
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "Valproic acid" in MCE Product Catalog:
69
69 Publications Verification
Synonyms: VPA; 2-Propylpentanoic acid; Dipropylacetic acid
69
69 Publications Verification
Synonyms: Sodium Valproate; VPA sodium; 2-Propylpentanoic acid sodium
1
1 Cited Publications
Synonyms: VPA-d4; 2-Propylpentanoic acid-d4
Target:
Research Areas:
Valpromide is an amide derivative of Valproic acid (HY-10585) and an orally active epoxide hydrolase inhibitor that can cross the blood-brain barrier. Valpromide has antiepileptic, anticonvulsant, and antipsychotic effects. Valpromide also exhibits antiviral activity and can inhibit the reactivation of the EBV lytic cycle .
Synonyms: VPA (Standard); 2-Propylpentanoic acid (Standard); Dipropylacetic acid (Standard)
Target:
Reference Standards Organoid HDAC Autophagy Mitophagy HIV Notch Apoptosis Endogenous Metabolite
Research Areas:
Valproic acid (Dipropylacetic Acid) (Standard) is an analytical standard for valproic acid. This product is intended for research and analytical applications. Valproic acid is an orally active HDAC inhibitor (IC50=0.5-2 mM), inhibits the activity of HDAC1 (IC50=400 μM), and induces the degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits the proliferation of small cell lung cancer (SCLC) cells. Valproic acid is used in the study of epilepsy, bipolar disorder, metabolic diseases, HIV infection, and migraine .
Synonyms: VPA-d6; 2-Propylpentanoic acid-d6
Target:
Research Areas:
(±)-2-Propyl-4-pentenoic acid (4-en-VPA) is a major toxic metabolite of Valproic acid. (±)-2-Propyl-4-pentenoic acid exhibits neuroteratogenicity .
Synonyms: VPA-d15; 2-Propylpentanoic acid-d15
Target:
Research Areas:
Valproic acid impurity 1 is an impurity of Valproic acid (HY-10585).
Cat. No.: HY-10585AR
CAS No.: 1069-66-5
Synonyms: Sodium Valproate (Standard); VPA sodium (Standard); 2-Propylpentanoic acid sodium (Standard)
Cat. No.: HY-10585S4
CAS No.: 345909-03-7
Synonyms: VPA-d4-1; 2-Propylpentanoic acid-d4-1
Cat. No.: HY-10585B
CAS No.: 76584-70-8
Synonyms: Sodium Valproate (2:1); VPA sodium (2:1); 2-Propylpentanoic acid sodium (2:1)
Target:
Cat. No.: HY-W400496
CAS No.: 60113-83-9
Valproic acid β-D-glucuronide is the major urinary metabolite of Valproic acid (HY-10585) .
Synonyms: (±)-2-Hexyl-4-pentynoic acid
Research Areas:
2-Hexyl-4-pentynoic acid ((±)-2-Hexyl-4-pentynoic acid), a Valproic acid (HY-10585) derivative, exhibits potential roles of HDAC inhibition (IC50 = 13 μM) and HSP70 induction. 2-Hexyl-4-pentynoic acid causes histone hyperacetylation and protect against glutamate-induced excitotoxicity in cultured neurons. 2-Hexyl-4-pentynoic acid can be used for the study of breast carcinoma. 2-Hexyl-4-pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
Cat. No.: HY-W794759
CAS No.: 62959-43-7
Synonyms: Magnesium valproate; VPA magnesium; 2-Propylpentanoic acid magnesium
Research Areas:
Valproic acid magnesium (Magnesium valproate) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM. Valproic acid magnesium inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid magnesium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid magnesium is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .
Cat. No.: HY-10585AS1
Purity: 96.45%
Synonyms: Sodium Valproate-d14; VPA-d14 sodium; 2-Propylpentanoic acid-d14 sodium
Cat. No.: HY-10585AS
CAS No.: 1189994-89-5
Synonyms: Sodium Valproate-d7; VPA-d7 sodium; 2-Propylpentanoic acid-d7 sodium
Cat. No.: HY-10585S3
Synonyms: Sodium Valproate-d4; VPA-d4 sodium; 2-Propylpentanoic acid-d4 sodium
Cat. No.: HY-10585AG
CAS No.: 1069-66-5
Synonyms: Sodium Valproate (GMP); VPA sodium (GMP); 2-Propylpentanoic acid sodium (GMP)
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
